PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31579066-2	2019	The aim of the present study was to determine whether MDIG is involved in cisplatin (DDP) resistance in lung adenocarcinoma, and to investigate the associated molecular mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	85-88	ribosomal oxygenase 2	Homo sapiens	54-58	
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	81-84	ribosomal oxygenase 2	Homo sapiens	68-72	
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	81-84	ribosomal oxygenase 2	Homo sapiens	194-198	
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	252-255	ribosomal oxygenase 2	Homo sapiens	68-72	
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	252-255	ribosomal oxygenase 2	Homo sapiens	194-198	
31579066-5	2019	Overexpression of MDIG in A549 and A549/DDP cells led to an increase in the IC50 value, whereas silencing of MDIG led to a clear reduction in the IC50 value.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	40-43	ribosomal oxygenase 2	Homo sapiens	18-22	
31579066-6	2019	The overexpression of MDIG in the A549 and A549/DDP cells markedly upregulated the mRNA and protein expression levels of ABCB1, ABCC1, ABCG2, WNT family member 5A, WNT family member 3A and active beta-catenin, and these were markedly decreased following MDIG silencing.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	48-51	ribosomal oxygenase 2	Homo sapiens	22-26	
31579066-7	2019	Taken together, these results demonstrated that the DDP resistance of lung adenocarcinoma may be associated with an upregulation of MDIG expression, and that the expression levels of MDIG are positively associated with the degree of DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	52-55	ribosomal oxygenase 2	Homo sapiens	132-136	
31579066-7	2019	Taken together, these results demonstrated that the DDP resistance of lung adenocarcinoma may be associated with an upregulation of MDIG expression, and that the expression levels of MDIG are positively associated with the degree of DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	233-236	ribosomal oxygenase 2	Homo sapiens	183-187	
31579066-8	2019	Furthermore, MDIG promoted the expression of ABC transporters in tumor cells by activating the WNT/beta-catenin signaling pathway, which may, in turn, lead to DDP resistance in lung adenocarcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	159-162	ribosomal oxygenase 2	Homo sapiens	13-17