PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14708091-0 2003 Vanadium inhibits placental glutathione S-transferase (GST-P) positive foci in 1,2-dimethyl hydrazine induced rat colon carcinogenesis. Vanadium 0-8 hematopoietic prostaglandin D synthase Rattus norvegicus 28-53 20352315-6 2010 A vanadium-chromium interaction which affected the GST activity was also found. Vanadium 2-10 hematopoietic prostaglandin D synthase Rattus norvegicus 51-54 15868487-5 2005 Further, the biotransformation status of vanadium was ascertained measuring the drug metabolising enzymes, glutathione S-transferase (GST) and cytochrome P-450 (Cyt P-450). Vanadium 41-49 hematopoietic prostaglandin D synthase Rattus norvegicus 107-132 15868487-5 2005 Further, the biotransformation status of vanadium was ascertained measuring the drug metabolising enzymes, glutathione S-transferase (GST) and cytochrome P-450 (Cyt P-450). Vanadium 41-49 hematopoietic prostaglandin D synthase Rattus norvegicus 134-137 15868487-6 2005 Significantly, there was an increase in glutathione S-transferase and cytochrome P-450 levels (p<0.01 and p<0.02, respectively) in rats supplemented with vanadium as compared to their carcinogen controls. Vanadium 160-168 hematopoietic prostaglandin D synthase Rattus norvegicus 40-65 26342819-5 2016 Supplemented high-fat diet with vanadium was shown to decrease (P < 0.05) activities of superoxide dismutase, total antioxidant capacity, glutathione-S transferase, and NAD(P)H/quinone oxidoreductase 1 (NQO1) and increase malondialdehyde content in the liver and kidney. Vanadium 32-40 hematopoietic prostaglandin D synthase Rattus norvegicus 141-166 24856383-11 2014 Vanadium treatment significantly reduced the elevated activities of GR, GPx, GST compared with the diabetic group whereas the decreases in CAT, SOD, CA, G6PD and LDH activities were insignificant. Vanadium 0-8 hematopoietic prostaglandin D synthase Rattus norvegicus 77-80 15151625-0 2004 Combined supplementation of vanadium and beta-carotene suppresses placental glutathione S-transferase-positive foci and enhances antioxidant functions during the inhibition of diethylnitrosamine-induced rat liver carcinogenesis. Vanadium 28-36 hematopoietic prostaglandin D synthase Rattus norvegicus 76-101 21533393-0 1997 Vanadium-mediated suppression of diethylnitrosamine-induced chromosomal aberrations in rat hepatocytes and its correlation with induction of hepatic glutathione and glutathione S-transferase. Vanadium 0-8 hematopoietic prostaglandin D synthase Rattus norvegicus 165-190 21533393-6 1997 Rats given injection of bromosulfophthalein (250 mg/kg), a substrate inhibitor of glutathione S-transferase (GST), 0.5 h before DENA treatment displayed a prominent suppression of the protective effect of vanadium on DENA-induced CA. Vanadium 205-213 hematopoietic prostaglandin D synthase Rattus norvegicus 82-107 21533393-6 1997 Rats given injection of bromosulfophthalein (250 mg/kg), a substrate inhibitor of glutathione S-transferase (GST), 0.5 h before DENA treatment displayed a prominent suppression of the protective effect of vanadium on DENA-induced CA. Vanadium 205-213 hematopoietic prostaglandin D synthase Rattus norvegicus 109-112 21533393-11 1997 The anticlastogenic effect of vanadium was found to be parallel to its ability to induce the activity of hepatic GST with a concurrent induction of hepatic GSH pool which were rather decreased in DENA control group. Vanadium 30-38 hematopoietic prostaglandin D synthase Rattus norvegicus 113-116 21533393-12 1997 The results of this study, thus, provide evidence that vanadium-dependent induction of GSH-mediated GST-catalyzed detoxificational capacity of the host is presumably related to its suppressive effect against CA. Vanadium 55-63 hematopoietic prostaglandin D synthase Rattus norvegicus 100-103 9398947-0 1995 Time course effects of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity. Vanadium 23-31 hematopoietic prostaglandin D synthase Rattus norvegicus 86-111 9398947-1 1995 The influence of vanadium, an important dietary micronutrient, was evaluated on the cytosolic reduced glutathione (GSH) content and glutathione S-transferase (GST) activity in several rat target tissues. Vanadium 17-25 hematopoietic prostaglandin D synthase Rattus norvegicus 132-157 9398947-2 1995 Supplementation of drinking water with vanadium at the level of 0.2 or 0.5 ppm for 4, 8, or 12 wk was found to increase the GSH level with a concomitant elevation in GST activity in the liver followed by small intestine mucosa, large intestine mucosa, and kidney. Vanadium 39-47 hematopoietic prostaglandin D synthase Rattus norvegicus 166-169 9398947-5 1995 The levels of vanadium that were found to increase the content of GSH and activity of GST in the liver, intestine, and kidney did not exert any toxic manifestation as evidenced from water and food consumption as well as the growth responses of the experimental animals. Vanadium 14-22 hematopoietic prostaglandin D synthase Rattus norvegicus 86-89 9398947-7 1995 All these results clearly indicate that vanadium under the doses employed in our study has a significant inducing role on GSH content with a concurrent elevation in GST activity in the liver and specific extrahepatic tissues without any apparent sign of cytotoxicity. Vanadium 40-48 hematopoietic prostaglandin D synthase Rattus norvegicus 165-168 9398947-9 1995 In addition, since the ability to afford an increment in the endogenous GSH-GST pool by anticarcinogenic natural substances has been found to correlate with their activity to inhibit neoplastic transformation, the trace element vanadium may be considered as a novel anticancer agent. Vanadium 228-236 hematopoietic prostaglandin D synthase Rattus norvegicus 76-79 11191639-0 2000 Combined supplementation of vanadium and 1alpha,25-dihydroxyvitamin D3 inhibit placental glutathione S-transferase positive foci in rat liver carcinogenesis. Vanadium 28-36 hematopoietic prostaglandin D synthase Rattus norvegicus 89-114