PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25728771-9 2015 In this manner, the CtBP co-repressor complex is recruited to, and silences, the E-cadherin promoter by inducing chromatin modifications. ctbp 20-24 cadherin 1 Homo sapiens 81-91 15542832-0 2004 Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene. ctbp 102-106 cadherin 1 Homo sapiens 134-144 21315774-5 2011 Since the E-cadherin promoter is a target of CtBP-mediated repression, the relationship between ataxin-1 and the E-cadherin promoter was investigated. ctbp 45-49 cadherin 1 Homo sapiens 10-20 18086895-1 2008 CtBP is a transcriptional corepressor with tumorigenic potential that targets the promoter of the tumor suppressor gene E-cadherin. ctbp 0-4 cadherin 1 Homo sapiens 120-130 18086895-2 2008 Pnn/DRS (Pnn) is a "nuclear speckle"-associated protein involved in mRNA processing as well as transcriptional regulation of E-cadherin via its binding to CtBP. ctbp 155-159 cadherin 1 Homo sapiens 125-135 18086895-3 2008 Here, we show that CtBP can recruit Pnn to CtBP-associated complexes, resulting in Pnn-dependent chromatin remodeling at the E-cadherin promoter. ctbp 19-23 cadherin 1 Homo sapiens 125-135 18086895-3 2008 Here, we show that CtBP can recruit Pnn to CtBP-associated complexes, resulting in Pnn-dependent chromatin remodeling at the E-cadherin promoter. ctbp 43-47 cadherin 1 Homo sapiens 125-135 17379597-10 2007 The inhibition of BCoR-L1 expression by RNA-mediated interference results in derepression of E-cadherin in cells that do not normally express E-cadherin, indicating that BCoR-L1 contributes to the repression of an authentic endogenous CtBP target. ctbp 235-239 cadherin 1 Homo sapiens 93-103 16804902-9 2006 However, when CtBP was strongly expressed, ZEB1 was inversely correlated with CDH1 (r = -0.39; p = 0.053). ctbp 14-18 cadherin 1 Homo sapiens 78-82 16740659-2 2006 In this study, we found that hypoxia increased free NADH levels in cancer cells, promoting CtBP recruitment to the E-cadherin promoter. ctbp 91-95 cadherin 1 Homo sapiens 115-125 16740659-4 2006 Furthermore, hypoxia repressed E-cadherin gene expression and increased tumor cell migration, effects that were blocked by CtBP knockdown. ctbp 123-127 cadherin 1 Homo sapiens 31-41