PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26825642-1	2016	Human hepatic carboxylesterase 1 and 2 (CES1 and CES2) are important for the disposition of ester- and amide-bond-containing pharmaceuticals and environmental chemicals.	Amides	103-108	carboxylesterase 2	Homo sapiens	49-53	
30466609-1	2018	BACKGROUND: Carboxylesterases (CEs) belong to the serine hydrolase family, and are in charge of hydrolyzing chemicals with carboxylic acid ester and amide functional groups via Ser-His-Glu.	Amides	149-154	carboxylesterase 2	Homo sapiens	12-29	
15100172-1	2004	Carboxylesterases metabolize ester, thioester, carbamate, and amide compounds to more soluble acid, alcohol, and amine products.	Amides	62-67	carboxylesterase 2	Homo sapiens	0-17	
21237253-1	2011	Carboxylesterases constitute a class of enzymes that hydrolyze drugs containing such functional groups as carboxylic acid ester, amide, and thioester.	Amides	129-134	carboxylesterase 2	Homo sapiens	0-17	
26900660-1	2016	Human carboxylesterase 2 (hCE2), one of the major carboxylesterases in the human intestine and various tumour tissues, plays important roles in the oral bioavailability and treatment outcomes of ester- or amide-containing drugs or prodrugs, such as anticancer agents CPT-11 (irinotecan) and LY2334737 (gemcitabine).	Amides	205-210	carboxylesterase 2	Homo sapiens	6-24	
26900660-1	2016	Human carboxylesterase 2 (hCE2), one of the major carboxylesterases in the human intestine and various tumour tissues, plays important roles in the oral bioavailability and treatment outcomes of ester- or amide-containing drugs or prodrugs, such as anticancer agents CPT-11 (irinotecan) and LY2334737 (gemcitabine).	Amides	205-210	carboxylesterase 2	Homo sapiens	26-30	
24988246-1	2014	Human carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are serine esterases responsible for the hydrolysis of ester and amide bonds present in a number of pharmaceutical products.	Amides	127-132	carboxylesterase 2	Homo sapiens	36-54	
24988246-1	2014	Human carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are serine esterases responsible for the hydrolysis of ester and amide bonds present in a number of pharmaceutical products.	Amides	127-132	carboxylesterase 2	Homo sapiens	56-60	
12835618-1	2003	Carboxylesterases are a broad class of enzymes important in the detoxification of many ester- or amide-bond containing xenobiotics.	Amides	97-102	carboxylesterase 2	Homo sapiens	0-17	
9300133-0	1997	Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver.	Amides	33-38	carboxylesterase 2	Homo sapiens	50-67