PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1587797-11 1992 Furthermore, when the CDP-choline pathway was mutationally blocked, choline did not affect INO1 expression, indicating that the metabolism of choline via the CDP-choline pathway is required for INO1 repression. Cytidine Diphosphate Choline 22-33 inositol-3-phosphate synthase INO1 Saccharomyces cerevisiae S288C 194-198 15560781-3 2004 The INO1 gene is deregulated (derepressed when inositol is present) under the conditions of increased phosphatidylcholine (PtdCho) turnover, as occurs in the sec14Delta cki1Delta strain (SEC14 encodes the major yeast phosphatidylinositol transfer protein; CKI1 encodes choline kinase of the cytidine diphosphate choline pathway of PtdCho biosynthesis). Cytidine Diphosphate Choline 291-319 inositol-3-phosphate synthase INO1 Saccharomyces cerevisiae S288C 4-8