PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30327144-0	2018	Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2.	sulindac sulfone	0-16	voltage dependent anion channel 1	Homo sapiens	89-128	
30327144-6	2018	we identified mitochondrial outer membrane proteins voltage-dependent anion channel (VDAC) 1 and VDAC2 as novel molecular targets of sulindac sulfone, and sulindac sulfone directly bound to both VDAC1 and VDAC2.	sulindac sulfone	133-149	voltage dependent anion channel 1	Homo sapiens	52-92	
30327144-6	2018	we identified mitochondrial outer membrane proteins voltage-dependent anion channel (VDAC) 1 and VDAC2 as novel molecular targets of sulindac sulfone, and sulindac sulfone directly bound to both VDAC1 and VDAC2.	sulindac sulfone	155-171	voltage dependent anion channel 1	Homo sapiens	195-200	
30327144-9	2018	Interestingly, these effects were consistent with those of sulindac sulfone against human colon cancer cells, suggesting that sulindac sulfone negatively regulates the function of VDAC1 and VDAC2.	sulindac sulfone	126-142	voltage dependent anion channel 1	Homo sapiens	180-185	
30327144-10	2018	In the present study, our data suggested that VDAC1 and VDAC2 are direct targets of sulindac sulfone which suppresses the mTORC1 pathway and induces G1 arrest.	sulindac sulfone	84-100	voltage dependent anion channel 1	Homo sapiens	46-51