PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34554935-1 2021 OBJECTIVES: This study was to explore the effects of teramethylpyrazine (TMP) administered in conjunction with neural stem cell transplantation on motor function, pathological lesions and the Janus kinase (JAK)2/signal transducer and activator of transcription 3 signal transduction pathway in rats following acute spinal cord injury (SCI). tmp 73-76 Janus kinase 2 Rattus norvegicus 192-211 34554935-9 2021 The expression of p-JAK2 in the NSCs+TMP group was relatively lower than the model and NSCs groups (P < 0.05). tmp 37-40 Janus kinase 2 Rattus norvegicus 20-24 34554935-10 2021 CONCLUSIONS: In rats with SCI, NSCs+TMP effectively improved motor function and offered spinal cord protection by increasing BDNF and decreasing Nogo-A levels, as well as inhibiting the JAK2/STAT3 signal transduction pathway, suggesting that TMP could be a useful agent in NSCs transplantation in the treatment of SCI. tmp 36-39 Janus kinase 2 Rattus norvegicus 186-190 34554935-10 2021 CONCLUSIONS: In rats with SCI, NSCs+TMP effectively improved motor function and offered spinal cord protection by increasing BDNF and decreasing Nogo-A levels, as well as inhibiting the JAK2/STAT3 signal transduction pathway, suggesting that TMP could be a useful agent in NSCs transplantation in the treatment of SCI. tmp 242-245 Janus kinase 2 Rattus norvegicus 186-190