PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30829081-0 2019 Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase. methoctramine 81-94 spermine oxidase Mus musculus 63-79 30829081-3 2019 Methoctramine (10), a well-known muscarinic M2 receptor antagonist, emerged as the most potent competitive PAOX inhibitor known so far (Ki = 10 nM), endowed with very good selectivity compared with SMOX (Ki=1.2 muM vs SMOX). methoctramine 0-13 spermine oxidase Mus musculus 218-222 30829081-5 2019 Methoctramine is a very promising tool in the design of drugs targeting the polyamine catabolism pathway, both to understand the physio-pathological role of PAOX vs SMOX and for pharmacological applications, being the polyamine pathway involved in various pathologies. methoctramine 0-13 spermine oxidase Mus musculus 165-169