PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26075729-0	2015	Palmitate Inhibits SIRT1-Dependent BMAL1/CLOCK Interaction and Disrupts Circadian Gene Oscillations in Hepatocytes.	Palmitates	0-9	clock circadian regulator	Homo sapiens	41-46	
31613643-10	2020	Circadian time-course studies revealed that core clock genes oscillate over time (P<0.05), with BMAL1, CIART, CRY2, DBP, PER1 and PER3 expression profiles altered by palmitate treatment.	Palmitates	169-178	clock circadian regulator	Homo sapiens	49-54	
31613643-12	2020	Palmitate exposure disrupts clock gene expression in myotubes, indicating dyslipidemia directly alters the circadian program.	Palmitates	0-9	clock circadian regulator	Homo sapiens	28-33	
26075729-3	2015	Here we presented evidence that the molecular clock is a novel target of palmitate in hepatocytes.	Palmitates	73-82	clock circadian regulator	Homo sapiens	46-51	
26075729-4	2015	Palmitate exposure at low dose inhibits the molecular clock activity and suppresses the cyclic expression of circadian targets including Dbp, Nr1d1 and Per2 in hepatocytes.	Palmitates	0-9	clock circadian regulator	Homo sapiens	54-59	
26075729-7	2015	Furthermore, we showed that SIRT1 activators could reverse the inhibitory action of palmitate on BMAL1-CLOCK interaction and the clock gene expression, whereas inhibitors of NAD synthesis mimic the palmitate effects on the clock function.	Palmitates	84-93	clock circadian regulator	Homo sapiens	103-108	
26075729-7	2015	Furthermore, we showed that SIRT1 activators could reverse the inhibitory action of palmitate on BMAL1-CLOCK interaction and the clock gene expression, whereas inhibitors of NAD synthesis mimic the palmitate effects on the clock function.	Palmitates	84-93	clock circadian regulator	Homo sapiens	129-134	
26075729-7	2015	Furthermore, we showed that SIRT1 activators could reverse the inhibitory action of palmitate on BMAL1-CLOCK interaction and the clock gene expression, whereas inhibitors of NAD synthesis mimic the palmitate effects on the clock function.	Palmitates	198-207	clock circadian regulator	Homo sapiens	223-228	
26075729-8	2015	In summary, our findings demonstrated that palmitate inhibits the clock function by suppressing SIRT1 function in hepatocytes.	Palmitates	43-52	clock circadian regulator	Homo sapiens	66-71