PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30620997-7 2019 ZnO NRs and ZnO Mini-NRs significantly promoted the expression of ER stress genes HSPA5, DDIT3, XBP-1s and apoptotic gene CASP3, whereas PA also modestly promoted the expression of HSPA5, DDIT3 and CASP3. Zinc Oxide 0-3 X-box binding protein 1 Homo sapiens 96-101 30620997-7 2019 ZnO NRs and ZnO Mini-NRs significantly promoted the expression of ER stress genes HSPA5, DDIT3, XBP-1s and apoptotic gene CASP3, whereas PA also modestly promoted the expression of HSPA5, DDIT3 and CASP3. Zinc Oxide 12-15 X-box binding protein 1 Homo sapiens 96-101 29691881-7 2018 Exposure to ZnO NPs at 3 hours induced the expression of endoplasmic reticulum stress markers DDIT3 and XBP-1 s, which was suppressed by H3. Zinc Oxide 12-15 X-box binding protein 1 Homo sapiens 104-109 24490819-5 2014 More importantly, ZnO NPs at noncytotoxic concentration, but not CeO2 NPs, can induce significant cellular ER stress response with higher expression of spliced xbp-1, chop, and caspase-12 at the mRNA level, and associated ER marker proteins including BiP, Chop, GADD34, p-PERK, p-eIF2alpha, and cleaved Caspase-12 at the protein levels. Zinc Oxide 18-21 X-box binding protein 1 Homo sapiens 160-165