PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20546814-10 2010 Our results also showed that deferoxamine attenuated rotenone-induced apoptosis, which was blocked when HIF-1 alpha or autophagy related gene Beclin 1 was suppressed. Rotenone 53-61 beclin 1 Homo sapiens 142-150 18032788-7 2007 Blocking the expression of autophagic genes (beclin 1 and ATG5) by siRNAs or using the autophagy inhibitor 3-methyladenine (3-MA) decreased cell death that was induced by rotenone or TTFA. Rotenone 171-179 beclin 1 Homo sapiens 45-53 30106049-6 2018 Western blot assays showed that BCL-2 and Beclin 1 levels were markedly higher in the genistein group than in the rotenone group. Rotenone 114-122 beclin 1 Homo sapiens 42-50 28137648-8 2017 Rotenone enhanced mTOR expression and suppressed Beclin-1 expression, indicating suppression of the autophagic system. Rotenone 0-8 beclin 1 Homo sapiens 49-57 25078626-10 2014 Rotenone inhibited autophagy, as indicated by decreased beclin-1 levels and increased mTOR levels, and this effect was reversed by calcitriol treatment. Rotenone 0-8 beclin 1 Homo sapiens 56-64 25078626-11 2014 DISCUSSION: Calcitriol protects against rotenone-induced neurotoxicity in SH-SY5Y cells by enhancing autophagy signaling pathways such as those involving LC3 and beclin-1. Rotenone 40-48 beclin 1 Homo sapiens 162-170 26156288-10 2016 Rotenone enhanced mTOR expression and suppressed Beclin-1 expression, indicating suppression of the autophagy system. Rotenone 0-8 beclin 1 Homo sapiens 49-57 26960433-3 2016 Using a rotenone-inducible cellular model of PD, we observed that a short exposure to rotenone (0.5 muM) resulted in impaired autophagic flux through activation of a Nox2 dependent Src/PI3K/Akt axis, with a consequent disruption of a Beclin1-VPS34 interaction that was independent of mTORC1 activity. Rotenone 86-94 beclin 1 Homo sapiens 234-241