PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21701161-7 2011 They regulated the intrinsic mitochondrial cell death signaling pathway and modulated activation of caspases, Bax, iNOS, p53, NF-kappaB, and mitogen-activated protein kinases (p38 and JNK) through different reactive oxygen and nitrosative species. reactive oxygen 207-222 mitogen-activated protein kinase 8 Homo sapiens 184-187 21038848-0 2010 Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen. reactive oxygen 104-119 mitogen-activated protein kinase 8 Homo sapiens 88-91 17209006-1 2007 c-Jun NH(2)-terminal kinase (JNK), a member of the MAPK family of protein kinases, is a stress-response kinase that is activated by proinflammatory cytokines and growth factors coupled to membrane receptors or through nonreceptor pathways by stimuli such as heat shock, UV irradiation, protein synthesis inhibitors, and conditions that elevate the levels of reactive oxygen intermediates (ROI). reactive oxygen 358-373 mitogen-activated protein kinase 8 Homo sapiens 0-27 17209006-1 2007 c-Jun NH(2)-terminal kinase (JNK), a member of the MAPK family of protein kinases, is a stress-response kinase that is activated by proinflammatory cytokines and growth factors coupled to membrane receptors or through nonreceptor pathways by stimuli such as heat shock, UV irradiation, protein synthesis inhibitors, and conditions that elevate the levels of reactive oxygen intermediates (ROI). reactive oxygen 358-373 mitogen-activated protein kinase 8 Homo sapiens 29-32 18728404-0 2008 The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells. reactive oxygen 87-102 mitogen-activated protein kinase 8 Homo sapiens 4-7