PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12614912-4 2003 In addition, tetrahydropapaveroline inhibited the activity of TPH, prepared from the P815 cells (P815-TPH), with the IC(50) value of 8.4 microM. Tetrahydropapaveroline 13-35 tryptophan hydroxylase 1 Mus musculus 62-65 12614912-4 2003 In addition, tetrahydropapaveroline inhibited the activity of TPH, prepared from the P815 cells (P815-TPH), with the IC(50) value of 8.4 microM. Tetrahydropapaveroline 13-35 tryptophan hydroxylase 1 Mus musculus 102-105 12614912-5 2003 Inhibition of P815-TPH by tetrahydropapaveroline was found to be non-competitive both with the substrate L-tryptophan and with the cofactor DL-6-methyl-5,6,7,8-tetrahydropterine. Tetrahydropapaveroline 26-48 tryptophan hydroxylase 1 Mus musculus 19-22 12614912-7 2003 These data indicate that tetrahydropapaveroline leads to a decrease in serotonin content by inhibiting TPH activity in P815 cells. Tetrahydropapaveroline 25-47 tryptophan hydroxylase 1 Mus musculus 103-106