PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21953684-7	2014	Benzene metabolites could not influence HaeIII DNMT activity except that 1,4-benzoquinone shows significantly inhibiting effect on enzymatic methylation reaction at concentrations of 5 muM (p < 0.05).	quinone	73-89	latexin	Homo sapiens	185-188	
29638121-6	2018	We also developed bacterial-selective prodrugs (reductively activated quinone-alkyloxycarbonyloxymethyl moiety) to afford HP 87, which demonstrated excellent antibacterial and biofilm eradication activities against MRSA BAA-1707 (MIC = 0.15 muM, MBEC = 12.5 muM).	quinone	70-77	latexin	Homo sapiens	241-244	
29638121-6	2018	We also developed bacterial-selective prodrugs (reductively activated quinone-alkyloxycarbonyloxymethyl moiety) to afford HP 87, which demonstrated excellent antibacterial and biofilm eradication activities against MRSA BAA-1707 (MIC = 0.15 muM, MBEC = 12.5 muM).	quinone	70-77	latexin	Homo sapiens	258-261	
28456030-8	2017	These values are comparable to those recorded for 1,4-benzoquinone of 4.82 muM (MAO-A) and 10.2 muM (MAO-B).	quinone	50-66	latexin	Homo sapiens	75-78	
21953684-8	2014	These results suggest that benzene metabolites, hydroquinone, and 1,4-benzoquinone can disrupt global DNA methylation, and the potential epigenetic mechanism by which that global DNA hypomethylation induced by 1,4-benzoquinone may work through the inhibiting effects of DNMT activity at 10 muM (p < 0.05).	quinone	66-82	latexin	Homo sapiens	290-293	
21953684-8	2014	These results suggest that benzene metabolites, hydroquinone, and 1,4-benzoquinone can disrupt global DNA methylation, and the potential epigenetic mechanism by which that global DNA hypomethylation induced by 1,4-benzoquinone may work through the inhibiting effects of DNMT activity at 10 muM (p < 0.05).	quinone	210-226	latexin	Homo sapiens	290-293	
21035322-3	2011	The biosensor also works well in the second generation biosensing mode with p-benzoquinone (BQ) or ferrocene monocarboxylic acid (Fc) as an artificial mediator, with greatly broadened linear detection ranges (2.0 muM-48.0 mM for BQ and 2.0 muM-16.0 mM for Fc) and up to mA cm(-2)-scale glucose-saturated current density.	quinone	76-90	latexin	Homo sapiens	213-216	
22910835-8	2012	A linear response was obtained for studied quinone concentrations in the range of 0.05-50 muM for 1,4-naphthquinone and of 0.05-150 muM for 2-methyl-1,4-naphthoquinone (menadione) and 9,10-anthraquinone with detection limit (blank + 3SD) of 0.01 muM.	quinone	43-50	latexin	Homo sapiens	90-93	
22910835-8	2012	A linear response was obtained for studied quinone concentrations in the range of 0.05-50 muM for 1,4-naphthquinone and of 0.05-150 muM for 2-methyl-1,4-naphthoquinone (menadione) and 9,10-anthraquinone with detection limit (blank + 3SD) of 0.01 muM.	quinone	43-50	latexin	Homo sapiens	132-135	
22910835-8	2012	A linear response was obtained for studied quinone concentrations in the range of 0.05-50 muM for 1,4-naphthquinone and of 0.05-150 muM for 2-methyl-1,4-naphthoquinone (menadione) and 9,10-anthraquinone with detection limit (blank + 3SD) of 0.01 muM.	quinone	43-50	latexin	Homo sapiens	132-135	
21570285-2	2011	Most of these compounds show selective action favored to human cancer cell lines over normal cell lines, and compound 9 with bis-terminal benzoquinone functionality exhibits an IC(50)=0.40 muM against MCF7 cell lines.	quinone	138-150	latexin	Homo sapiens	189-192	
21240422-3	2011	The principle of catechol estimation was based on the reduction of biocatalytically liberated quinone species at +0.2 V versus Ag/AgCl (3 M KCl), with good stability, sensitivity, and featuring a low detection limit (about 0.002 muM) and wide linear range (0.005 muM-120 muM).	quinone	94-101	latexin	Homo sapiens	229-232	
21240422-3	2011	The principle of catechol estimation was based on the reduction of biocatalytically liberated quinone species at +0.2 V versus Ag/AgCl (3 M KCl), with good stability, sensitivity, and featuring a low detection limit (about 0.002 muM) and wide linear range (0.005 muM-120 muM).	quinone	94-101	latexin	Homo sapiens	263-266	
21240422-3	2011	The principle of catechol estimation was based on the reduction of biocatalytically liberated quinone species at +0.2 V versus Ag/AgCl (3 M KCl), with good stability, sensitivity, and featuring a low detection limit (about 0.002 muM) and wide linear range (0.005 muM-120 muM).	quinone	94-101	latexin	Homo sapiens	263-266	
21035322-3	2011	The biosensor also works well in the second generation biosensing mode with p-benzoquinone (BQ) or ferrocene monocarboxylic acid (Fc) as an artificial mediator, with greatly broadened linear detection ranges (2.0 muM-48.0 mM for BQ and 2.0 muM-16.0 mM for Fc) and up to mA cm(-2)-scale glucose-saturated current density.	quinone	76-90	latexin	Homo sapiens	240-243	
21035322-3	2011	The biosensor also works well in the second generation biosensing mode with p-benzoquinone (BQ) or ferrocene monocarboxylic acid (Fc) as an artificial mediator, with greatly broadened linear detection ranges (2.0 muM-48.0 mM for BQ and 2.0 muM-16.0 mM for Fc) and up to mA cm(-2)-scale glucose-saturated current density.	quinone	92-94	latexin	Homo sapiens	213-216	
21035322-3	2011	The biosensor also works well in the second generation biosensing mode with p-benzoquinone (BQ) or ferrocene monocarboxylic acid (Fc) as an artificial mediator, with greatly broadened linear detection ranges (2.0 muM-48.0 mM for BQ and 2.0 muM-16.0 mM for Fc) and up to mA cm(-2)-scale glucose-saturated current density.	quinone	92-94	latexin	Homo sapiens	240-243