PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10220560-3 1999 Doxorubicin, 1,4-naphthoquinone (NQ), and 1, 4-benzoquinone (BQ) are found to selectively and dose-dependently interact with a class of hyperreactive sulfhydryl groups localized on ryanodine-sensitive Ca2+ channels [ryanodine receptor (RyR)], and its associated protein, triadin, of skeletal type channels. quinone 42-59 ryanodine receptor 1 Homo sapiens 236-239 10220560-8 1999 These results provide evidence that nanomolar quinone selectively and reversibly alters the redox state of hyperreactive sulfhydryls localized in the RyR/Ca2+ channel complex, resulting in enhanced channel activation. quinone 46-53 ryanodine receptor 1 Homo sapiens 150-153