PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15950210-4	2005	In a previous study of quinone toxicity, this quinone, whose actions have been exclusively attributed to reactive oxygen species (ROS) generation, caused a reduction in the glycolytic activity of GAPDH under aerobic and anaerobic conditions, indicating indirect and possible direct actions on this enzyme.	quinone	23-30	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	196-201	
15950210-4	2005	In a previous study of quinone toxicity, this quinone, whose actions have been exclusively attributed to reactive oxygen species (ROS) generation, caused a reduction in the glycolytic activity of GAPDH under aerobic and anaerobic conditions, indicating indirect and possible direct actions on this enzyme.	quinone	46-53	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	196-201	
15950210-8	2005	This quinone, which is not considered an electrophile, inhibited GAPDH in a time-dependent manner, consistent with irreversible modification and comparable to the electrophilic actions of 1,4-benzoquinone (1,4-BQ).	quinone	5-12	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	65-70	
15950210-8	2005	This quinone, which is not considered an electrophile, inhibited GAPDH in a time-dependent manner, consistent with irreversible modification and comparable to the electrophilic actions of 1,4-benzoquinone (1,4-BQ).	quinone	206-212	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	65-70	
27856348-5	2016	When glyceraldehyde 3-phosphate dehydrogenase was exposed to the myeloperoxidase system with 5HIAA, quinone adducts were formed on the protein molecule.	quinone	100-107	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	5-45	
21827172-3	2011	GAPDH readily formed a covalent bond with 1,2-NQ through Cys152 at a low concentration (0.2 muM) in a cell-free system, but when human epithelial A549 cells were exposed to this quinone at 20 muM, only minimal binding was observed although extensive binding to numerous other cellular proteins occurred.	quinone	178-185	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	0-5