PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22517972-0 2012 Sequential metabolism of AMG 487, a novel CXCR3 antagonist, results in formation of quinone reactive metabolites that covalently modify CYP3A4 Cys239 and cause time-dependent inhibition of the enzyme. quinone 84-91 C-X-C motif chemokine receptor 3 Homo sapiens 42-47