PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31919413-0 2020 GSK3beta is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ. quinone 79-86 glycogen synthase kinase 3 alpha Homo sapiens 0-8 31919413-6 2020 Using the quinone DMNQ, a ROS generator, we demonstrate that GSK3beta is involved in the regulation of ROS-dependent necrosis. quinone 10-17 glycogen synthase kinase 3 alpha Homo sapiens 61-69 31919413-9 2020 During the quinone-induced pro-necrotic stress, GSK3beta gradually accumulates into the nucleus, before the collapse of the mitochondrial membrane potential. quinone 11-18 glycogen synthase kinase 3 alpha Homo sapiens 48-56 31919413-13 2020 In summary, GSK3beta by blunting the anti-oxidant response and particularly NQO1 and NQO2 expression, favors the appearance of necrosis in response to ROS, as generated by the quinone DMNQ. quinone 176-183 glycogen synthase kinase 3 alpha Homo sapiens 12-20