PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12007724-5 2002 Immunostaining for oxidative stress markers such as 4-hydroxy-2-nonenal (HNE)-modified proteins and heme oxygenase-1 revealed that probucol treatment decreased reactive oxygen species (ROS) in pancreatic islets of diabetic animals. Probucol 131-139 heme oxygenase 1 Mus musculus 100-116 31478560-11 2020 But the anti-inflammatory effect of PB on VSMCs was weakened significantly when HO-1 was inhibited by siRNA. Probucol 36-38 heme oxygenase 1 Mus musculus 80-84 31478560-13 2020 HO-1 plays a crucial role in anti-inflammatory effect of PB on VSMCs. Probucol 57-59 heme oxygenase 1 Mus musculus 0-4 31590160-6 2019 Moreover, Prob alleviated ROS and MDA levels by elevating SOD, GSH-PX and HO-1 mRNA and protein expressions, and improving plasmic and cerebral SOD and GSH-PX activities in D-gal treated mice. Probucol 10-14 heme oxygenase 1 Mus musculus 63-78