PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26174000-11 2016 The effect of beta-LG phenotype on the fatty acid composition and antioxidant capacity of milk is variable, which could partly be the result of a beta-LG phenotype x diet interaction. Fatty Acids 39-49 beta-lactoglobulin Bos taurus 14-21 29879410-0 2018 Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine beta-Lactoglobulin. Fatty Acids 75-85 beta-lactoglobulin Bos taurus 104-122 29391528-6 2018 Results suggest associations of PAEP with the content of C4:0, AACS with the content of fatty acids C4:0-C6:0, NCOA6 or ACSS2 with the longer chain fatty acids C6:0-C14:0, and FASN mainly associated with content of C14:0. Fatty Acids 88-99 beta-lactoglobulin Bos taurus 32-36 26174000-11 2016 The effect of beta-LG phenotype on the fatty acid composition and antioxidant capacity of milk is variable, which could partly be the result of a beta-LG phenotype x diet interaction. Fatty Acids 39-49 beta-lactoglobulin Bos taurus 146-153 26281976-1 2015 beta-Lactoglobulin (beta-LG) is a member of lipocalin superfamily of transporters for small hydrophobic molecules such as retinoids, fatty acids, drugs, and vitamins. Fatty Acids 133-144 beta-lactoglobulin Bos taurus 0-18 26281976-1 2015 beta-Lactoglobulin (beta-LG) is a member of lipocalin superfamily of transporters for small hydrophobic molecules such as retinoids, fatty acids, drugs, and vitamins. Fatty Acids 133-144 beta-lactoglobulin Bos taurus 20-27 22425630-0 2012 Structural and thermodynamic studies of binding saturated fatty acids to bovine beta-lactoglobulin. Fatty Acids 48-69 beta-lactoglobulin Bos taurus 80-98 26272099-0 2015 Factors affecting the interactions between beta-lactoglobulin and fatty acids as revealed in molecular dynamics simulations. Fatty Acids 66-77 beta-lactoglobulin Bos taurus 43-61 26272099-2 2015 Fatty acids (FAs), common hydrophobic molecules bound to BLG, are important sources of fuel for life because they yield large quantities of ATP when metabolized. Fatty Acids 0-11 beta-lactoglobulin Bos taurus 57-60 26272099-2 2015 Fatty acids (FAs), common hydrophobic molecules bound to BLG, are important sources of fuel for life because they yield large quantities of ATP when metabolized. Fatty Acids 13-16 beta-lactoglobulin Bos taurus 57-60 26272099-7 2015 In this work, we used hybrid steered molecular dynamics to accurately compute the binding free energies between BLG and the five saturated FAs of 8 to 16 carbon atoms. Fatty Acids 139-142 beta-lactoglobulin Bos taurus 112-115 24865819-3 2014 Bovine beta-lactoglobulin (betalg) is a lipocalin member that carries fatty acids (FAs) and other lipids in the cellular environment. Fatty Acids 70-81 beta-lactoglobulin Bos taurus 7-25 24865819-3 2014 Bovine beta-lactoglobulin (betalg) is a lipocalin member that carries fatty acids (FAs) and other lipids in the cellular environment. Fatty Acids 83-86 beta-lactoglobulin Bos taurus 7-25 25110551-0 2014 Bovine beta-lactoglobulin/fatty acid complexes: binding, structural, and biological properties. Fatty Acids 26-36 beta-lactoglobulin Bos taurus 7-25 25110551-5 2014 Structural changes modify the stoichiometry and the affinity of beta-lg for fatty acids and consequently the biological functions of the complex. Fatty Acids 76-87 beta-lactoglobulin Bos taurus 64-71 25110551-7 2014 These proteins affect beta-lg/fatty acids complex in whey given their competition with beta-lg for fatty acids. Fatty Acids 30-41 beta-lactoglobulin Bos taurus 22-29 25110551-7 2014 These proteins affect beta-lg/fatty acids complex in whey given their competition with beta-lg for fatty acids. Fatty Acids 30-41 beta-lactoglobulin Bos taurus 87-94 25110551-7 2014 These proteins affect beta-lg/fatty acids complex in whey given their competition with beta-lg for fatty acids. Fatty Acids 99-110 beta-lactoglobulin Bos taurus 22-29 25110551-7 2014 These proteins affect beta-lg/fatty acids complex in whey given their competition with beta-lg for fatty acids. Fatty Acids 99-110 beta-lactoglobulin Bos taurus 87-94 23684041-0 2013 beta-Lactoglobulin-linoleate complexes: In vitro digestion and the role of protein in fatty acid uptake. Fatty Acids 86-96 beta-lactoglobulin Bos taurus 0-18 23684041-1 2013 The dairy protein beta-lactoglobulin (BLG) is known to bind fatty acids such as the salt of the essential longchain fatty acid linoleic acid (cis,cis-9,12-octadecadienoic acid, n-6, 18:2). Fatty Acids 60-71 beta-lactoglobulin Bos taurus 18-36 23684041-1 2013 The dairy protein beta-lactoglobulin (BLG) is known to bind fatty acids such as the salt of the essential longchain fatty acid linoleic acid (cis,cis-9,12-octadecadienoic acid, n-6, 18:2). Fatty Acids 60-71 beta-lactoglobulin Bos taurus 38-41 23684041-7 2013 In conclusion, understanding interactions between linoleate and BLG could help to formulate foods with targeted fatty acid bioaccessibility and, therefore, aid in the development of food matrices with optimal bioactive efficacy. Fatty Acids 112-122 beta-lactoglobulin Bos taurus 64-67 22950964-1 2012 beta-Lactoglobulin (beta-LG) is a member of the lipocalin protein family involved in the transport of fatty acids and other small hydrophobic molecules. Fatty Acids 102-113 beta-lactoglobulin Bos taurus 0-18 22950964-1 2012 beta-Lactoglobulin (beta-LG) is a member of the lipocalin protein family involved in the transport of fatty acids and other small hydrophobic molecules. Fatty Acids 102-113 beta-lactoglobulin Bos taurus 20-27 22950964-3 2012 Continuous-wave and pulsed Fourier transform electron spin resonance (cw- and FT-EPR) spectroscopy and molecular dynamics (MD) simulation were combined to investigate the interaction of fatty acids with bovine beta-LG. Fatty Acids 186-197 beta-lactoglobulin Bos taurus 210-217 22950964-9 2012 The results highlight the dynamical features of fatty acids/beta-LG interaction. Fatty Acids 48-59 beta-lactoglobulin Bos taurus 60-67 21732322-3 2011 The biological function of beta-LG is not clear, but its potential role in carrying fatty acids through the digestive tract has been suggested. Fatty Acids 84-95 beta-lactoglobulin Bos taurus 27-34 19415669-7 2009 An alternative explanation may be that the lipids bind to a secondary fatty acid binding site in beta-Lg, thus blocking the action of proteases for steric reasons. Fatty Acids 70-80 beta-lactoglobulin Bos taurus 97-104 21506515-0 2011 Bound fatty acids modulate the sensitivity of bovine beta-lactoglobulin to chemical and physical denaturation. Fatty Acids 6-17 beta-lactoglobulin Bos taurus 53-71 21506515-1 2011 Fatty acids are the natural ligands associated with the bovine milk lipocalin, beta-lactoglobulin (BLG), and were identified by means of mass spectrometry. Fatty Acids 0-11 beta-lactoglobulin Bos taurus 79-97 21506515-1 2011 Fatty acids are the natural ligands associated with the bovine milk lipocalin, beta-lactoglobulin (BLG), and were identified by means of mass spectrometry. Fatty Acids 0-11 beta-lactoglobulin Bos taurus 99-102 20723666-1 2010 Beta-lactoglobulin (beta-LG) is a member of the lipocalin protein family and can bind a variety of hydrophobic molecules, such as fatty acids, in vitro. Fatty Acids 130-141 beta-lactoglobulin Bos taurus 20-27 11856834-2 2002 The biological function of BLG is not clear, but a potential role in carrying fatty acids through the digestive tract has been proposed. Fatty Acids 78-89 beta-lactoglobulin Bos taurus 27-30 16721656-3 2006 The presence of a fatty acid side chain in the dual probes was found to be required for binding to beta-lactoglobulin. Fatty Acids 18-28 beta-lactoglobulin Bos taurus 99-117 12876309-0 2003 Competitive binding of fatty acids and the fluorescent probe 1-8-anilinonaphthalene sulfonate to bovine beta-lactoglobulin. Fatty Acids 23-34 beta-lactoglobulin Bos taurus 104-122 12876309-1 2003 The use of spectroscopy in the study of fatty acids binding to bovine beta-lactoglobulin (BLG) appears to be a difficult task, as these acid compounds, assumed as the protein natural ligands, do not exhibit favorable optical response such as, for example, absorption or fluorescence. Fatty Acids 40-51 beta-lactoglobulin Bos taurus 70-88 12876309-1 2003 The use of spectroscopy in the study of fatty acids binding to bovine beta-lactoglobulin (BLG) appears to be a difficult task, as these acid compounds, assumed as the protein natural ligands, do not exhibit favorable optical response such as, for example, absorption or fluorescence. Fatty Acids 40-51 beta-lactoglobulin Bos taurus 90-93 12876309-2 2003 Therefore, the BLG fatty-acid equilibrium has been tackled by exploiting the competition between fatty acids and ANS, a widely used fluorescent hydrophobic probe, whose binding sites on the protein have been characterized recently. Fatty Acids 19-29 beta-lactoglobulin Bos taurus 15-18 12876309-2 2003 Therefore, the BLG fatty-acid equilibrium has been tackled by exploiting the competition between fatty acids and ANS, a widely used fluorescent hydrophobic probe, whose binding sites on the protein have been characterized recently. Fatty Acids 97-108 beta-lactoglobulin Bos taurus 15-18 10933500-1 2000 Bovine beta-lactoglobulin (BLG) in vivo has been found complexed with fatty acids, especially palmitic and oleic acid. Fatty Acids 70-81 beta-lactoglobulin Bos taurus 7-25 10933500-1 2000 Bovine beta-lactoglobulin (BLG) in vivo has been found complexed with fatty acids, especially palmitic and oleic acid. Fatty Acids 70-81 beta-lactoglobulin Bos taurus 27-30 9827560-1 1998 The X-ray structure of bovine beta-lactoglobulin with the ligand 12-bromododecanoic acid as a model for fatty acids has been determined at a resolution of 2.23 A in the trigonal lattice Z form. Fatty Acids 104-115 beta-lactoglobulin Bos taurus 30-48 2628426-0 1989 Interaction of fatty acids with beta-lactoglobulin and albumin from ruminant milk. Fatty Acids 15-26 beta-lactoglobulin Bos taurus 32-50 1739746-3 1992 Bovine beta-lactoglobulin displays only one high affinity binding site for fatty acids whose association constants for palmitic and oleic acids are 4.2 x 10(6) and 2.3 x 10(6) M-1, respectively. Fatty Acids 75-86 beta-lactoglobulin Bos taurus 7-25 1739746-5 1992 The existence of one high affinity binding site is in accordance with the amount of fatty acids naturally bound to beta-lactoglobulin isolated from milk. Fatty Acids 84-95 beta-lactoglobulin Bos taurus 115-133 1739746-9 1992 These results indicate that beta-lactoglobulin could participate in the digestion of milk lipids during the neonatal period by enhancing the activity of pregastric lipase through removal of the fatty acids that inhibit this enzyme. Fatty Acids 194-205 beta-lactoglobulin Bos taurus 28-46 2628426-1 1989 beta-Lactoglobulin isolated from milk of cow, sheep, and goat had about 0.5 mol of fatty acids bound per mol of monomer protein. Fatty Acids 83-94 beta-lactoglobulin Bos taurus 0-18 2628426-5 1989 Interaction of beta-lactoglobulin and albumin with insolubilized fatty acids showed some differences, suggesting different structures of the respective fatty acid binding sites. Fatty Acids 65-76 beta-lactoglobulin Bos taurus 15-33 2628426-5 1989 Interaction of beta-lactoglobulin and albumin with insolubilized fatty acids showed some differences, suggesting different structures of the respective fatty acid binding sites. Fatty Acids 65-75 beta-lactoglobulin Bos taurus 15-33 33842774-2 2021 beta-Lactoglobulin (BLG), the dominant whey protein in bovine milk, is well known to bind small molecules such as fatty acids, vitamins, and flavors, and to interact with neutral and anionic polysaccharides used in food and pharmaceuticals. Fatty Acids 114-125 beta-lactoglobulin Bos taurus 0-18 33842774-2 2021 beta-Lactoglobulin (BLG), the dominant whey protein in bovine milk, is well known to bind small molecules such as fatty acids, vitamins, and flavors, and to interact with neutral and anionic polysaccharides used in food and pharmaceuticals. Fatty Acids 114-125 beta-lactoglobulin Bos taurus 20-23