PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32326415-6 2020 Key genes involved in de novo fatty acid biosynthesis, elongation and desaturation were upregulated in AL such as ACLY, FASN, ME1, ELOVL6 and SCD. Fatty Acids 30-40 fatty acid synthase Sus scrofa 120-124 34760251-9 2021 Furthermore, the key proteins involved in fatty acid synthesis (ACACA and FASN) were identified, and their expression levels were verified (p < .05) using Western blotting. Fatty Acids 42-52 fatty acid synthase Sus scrofa 74-78 35409000-5 2022 Similarly, the abundance of fatty acid synthesis genes ACACA and FASN and transcription regulators SREBP1c and SREBP2 was elevated. Fatty Acids 28-38 fatty acid synthase Sus scrofa 65-69 31515844-8 2019 The joint analysis of GO terms and pathways revealed that methylation and gene expression of seven candidate genes were associated with BT; in particular, FASN plays a key role in fatty acid biosynthesis, and PEMT might be involved in estrogen regulation and the development of BT. Fatty Acids 180-190 fatty acid synthase Sus scrofa 155-159 31998401-7 2020 Fatty acid synthesis in pigs from the H-BCAA group was lower than those from the N-BCAA group with the down-regulation of lipogenic genes (ACACA, FASN, PPAR-r, SREBP-1c in ventral and dorsal fat, SREBP-1c in liver) and up-regulation of lipolysis genes (HSL, ATGL, CPT-1A, FABP4 in ventral fat, HSL in liver) (P < 0.05). Fatty Acids 0-10 fatty acid synthase Sus scrofa 146-150 31998401-8 2020 Similarly, fatty acid synthesis in pigs from the L-BCAA group was also lower than those from the N-BCAA group with the decrease of lipogenic genes (ACACA in ventral, ACACA and FASN in dorsal fat, ACACA, FASN, SREBP-1c in liver) and the increase of lipolysis genes (ATGL, CPT-1A CD36, FABP4 in ventral fat and HSL, ATGL, CPT-1A in dorsal fat, CPT-1A) (P < 0.05). Fatty Acids 11-21 fatty acid synthase Sus scrofa 176-180 31998401-8 2020 Similarly, fatty acid synthesis in pigs from the L-BCAA group was also lower than those from the N-BCAA group with the decrease of lipogenic genes (ACACA in ventral, ACACA and FASN in dorsal fat, ACACA, FASN, SREBP-1c in liver) and the increase of lipolysis genes (ATGL, CPT-1A CD36, FABP4 in ventral fat and HSL, ATGL, CPT-1A in dorsal fat, CPT-1A) (P < 0.05). Fatty Acids 11-21 fatty acid synthase Sus scrofa 203-207 28402008-6 2017 These regions not only replicated previously reported loci containing some candidate genes involved in fatty acid composition (fatty acid synthase and stearoyl-CoA desaturase) but also included several additional related loci. Fatty Acids 103-113 fatty acid synthase Sus scrofa 127-146 31727987-7 2019 The upregulation genes in pigs with higher backfat thickness were mainly involved in fatty acid synthesis, and included fatty acid synthase (FASN), glucokinase (GCK), phosphoglycerate dehydrogenase (PHGDH), and apolipoprotein A4 (APOA4). Fatty Acids 85-95 fatty acid synthase Sus scrofa 141-145 23957397-8 2013 A positive relationship was found between FAS abundance and the saturated fatty acids (SFAs), for Large White x Pietrain pigs, but not for the other breeds. Fatty Acids 64-85 fatty acid synthase Sus scrofa 42-45 28107461-10 2017 These results show that FASN exerts an effect on early embryonic development by regulating both fatty acid oxidation and the AKT pathway in pigs. Fatty Acids 96-106 fatty acid synthase Sus scrofa 24-28 26796620-7 2016 The genes ELOVL5, ELOVL6, ELOVL7, FASN, SCD and THRSP, which have functions that are directly relevant to fatty acid metabolism, are proximal to the top associated markers at six significant QTL. Fatty Acids 106-116 fatty acid synthase Sus scrofa 34-38 17555288-2 2007 Increased dietary fat or higher non-esterified fatty acids (NEFA) from starvation-induced mobilisation may enhance hepatic oxidation and decrease esterification of fatty acids by reducing the expression of the fatty acid synthase gene. Fatty Acids 47-58 fatty acid synthase Sus scrofa 210-229 23301040-7 2013 Cross-comparison analysis revealed that genes that regulate fatty acid biosynthesis (e.g., fatty acid synthase and stearoyl-CoA desaturase) are expressed at higher levels in Jinhua pigs whereas those that regulate myogenesis (e.g., myogenic factor 6 and forkhead box O1) are expressed at higher levels in Landrace pigs. Fatty Acids 60-70 fatty acid synthase Sus scrofa 91-110 17555288-2 2007 Increased dietary fat or higher non-esterified fatty acids (NEFA) from starvation-induced mobilisation may enhance hepatic oxidation and decrease esterification of fatty acids by reducing the expression of the fatty acid synthase gene. Fatty Acids 164-175 fatty acid synthase Sus scrofa 210-229