PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9924985-8 1998 In ras-transformed cells incubated with increasing concentrations of arachidonic acid, PLA2 activity was altered in parallel with the changes of the cellular content of this fatty acid. Fatty Acids 174-184 phospholipase A2, group IB, pancreas Mus musculus 87-91 9788614-2 1998 After phorbol ester treatment, AA is hydrolyzed from keratinocytes primarily by the cytosolic form of phospholipase A2 (cPLA2), which exhibited a strong substrate preference for phosphatidylcholine over phosphatidylethanolamine and AA over other fatty acids. Fatty Acids 246-257 phospholipase A2, group IB, pancreas Mus musculus 102-118 9548589-13 1998 In conclusion, keratinocytes express several forms of phospholipase A2 that differ in their substrate specificities and mechanisms of activation, resulting in distinct agonist-specific fatty acid release profiles. Fatty Acids 185-195 phospholipase A2, group IB, pancreas Mus musculus 54-70 8042988-1 1994 The selectivity of the intracellular 85 kDa phospholipase A2 (PLA2-85) towards fatty acids closely related to arachidonic acid has been investigated, using purified PLA2-85 from J774 cells and mixed phospholipids, dually acyl-chain-labelled in the sn-2 position. Fatty Acids 79-90 phospholipase A2, group IB, pancreas Mus musculus 44-60 9403693-2 1997 PLA2 enzymes release fatty acids and lysophospholipids, including the precursor of platelet-activating factor, PAF, from phospholipids. Fatty Acids 21-32 phospholipase A2, group IB, pancreas Mus musculus 0-4 1449818-3 1992 AA participates in a deacylation/reacylation cycle of membrane phospholipids in which the fatty acid is cleaved by phospholipase A2 and reesterified by acyltransferase. Fatty Acids 90-100 phospholipase A2, group IB, pancreas Mus musculus 115-131 1530793-7 1992 The consequence of the elevated PLA2 activity was examined by analysis of the fatty acids released from IL-1-treated cells. Fatty Acids 78-89 phospholipase A2, group IB, pancreas Mus musculus 32-36 3824415-4 1987 The microsomal PLA2 stimulated by these toxins had a high fatty acid specificity (C-2 position) toward arachidonic acid. Fatty Acids 58-68 phospholipase A2, group IB, pancreas Mus musculus 15-19 3021238-0 1986 Effect of cellular fatty acid composition on the phospholipase A2 activity of bone marrow-derived macrophages, and their ability to induce lucigenin-dependent chemiluminescence. Fatty Acids 19-29 phospholipase A2, group IB, pancreas Mus musculus 49-65 3021238-3 1986 The fatty acid composition of the cellular membranes directly modulates functional abilities of the macrophages such as the generation of superoxide anion and phospholipase A2 activity in response to phorbol ester and zymosan. Fatty Acids 4-14 phospholipase A2, group IB, pancreas Mus musculus 159-175 6237161-7 1984 The PC-binding proteins possessed a typical phospholipase A2 activity, which was maximal at pH 9.5, depended on Ca++, and was specific for cleavage of fatty acid from the sn-2 position of phosphatidylcholine. Fatty Acids 151-161 phospholipase A2, group IB, pancreas Mus musculus 44-60 30554008-4 2019 We report here that the ability of horse serum to support the self-renewal of multipotent murine hematopoietic progenitor FDCP-Mix cells is correlated to the concentration of specific fatty acid products of phospholipase A2 and more closely to the spectrum of eicosanoids generated by their further processing through cyclooxygenase and lipoxygenase pathways. Fatty Acids 184-194 phospholipase A2, group IB, pancreas Mus musculus 207-223 6804944-4 1982 Phosphatidylcholine-binding proteins possessed a typical phospholipase A2 activity (phosphatide 2-acylhydrolase, EC 3.1.1.4), which was maximal (10 mumol/min per mg of protein) at pH 9.5, depended on Ca2+, and was specific for cleavage of fatty acid from the C-2 position of the glycerol backbone of phosphatidylcholine. Fatty Acids 239-249 phospholipase A2, group IB, pancreas Mus musculus 57-73 29259680-1 2016 Within the phospholipase A2 (PLA2) superfamily that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 (sPLA2) enzymes comprise the largest family that contains 11 isoforms in mammals. Fatty Acids 86-97 phospholipase A2, group IB, pancreas Mus musculus 11-27 30546811-3 2018 Phospholipase A2 (PLA2) enzymes supply fatty acids and lysophospholipids from membrane phospholipids, thereby variably affecting cutaneous homeostasis. Fatty Acids 39-50 phospholipase A2, group IB, pancreas Mus musculus 0-16 30546811-3 2018 Phospholipase A2 (PLA2) enzymes supply fatty acids and lysophospholipids from membrane phospholipids, thereby variably affecting cutaneous homeostasis. Fatty Acids 39-50 phospholipase A2, group IB, pancreas Mus musculus 18-22 29259680-1 2016 Within the phospholipase A2 (PLA2) superfamily that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 (sPLA2) enzymes comprise the largest family that contains 11 isoforms in mammals. Fatty Acids 86-97 phospholipase A2, group IB, pancreas Mus musculus 29-33 29259680-1 2016 Within the phospholipase A2 (PLA2) superfamily that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 (sPLA2) enzymes comprise the largest family that contains 11 isoforms in mammals. Fatty Acids 86-97 phospholipase A2, group IB, pancreas Mus musculus 134-138 21746768-1 2011 Phospholipase A(2) (PLA(2)) catalyses the hydrolysis of the sn-2 position of glycerophospholipids to yield fatty acids and lysophospholipids. Fatty Acids 107-118 phospholipase A2, group IB, pancreas Mus musculus 0-18 25915851-8 2015 In conclusion, this metabolomic profiling approach in AdKO mice identified important targets of adiponectin action, including PLA2, to regulate lysophospholipid metabolism and omega-oxidation of fatty acids. Fatty Acids 195-206 phospholipase A2, group IB, pancreas Mus musculus 126-130 27769509-1 2016 Within the phospholipase A2 (PLA2) family that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, secreted PLA2 (sPLA2) enzymes comprise the largest group containing 11 isoforms in mammals. Fatty Acids 81-92 phospholipase A2, group IB, pancreas Mus musculus 11-27 27769509-1 2016 Within the phospholipase A2 (PLA2) family that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, secreted PLA2 (sPLA2) enzymes comprise the largest group containing 11 isoforms in mammals. Fatty Acids 81-92 phospholipase A2, group IB, pancreas Mus musculus 29-33 27769509-1 2016 Within the phospholipase A2 (PLA2) family that hydrolyzes phospholipids to yield fatty acids and lysophospholipids, secreted PLA2 (sPLA2) enzymes comprise the largest group containing 11 isoforms in mammals. Fatty Acids 81-92 phospholipase A2, group IB, pancreas Mus musculus 125-129 21746768-1 2011 Phospholipase A(2) (PLA(2)) catalyses the hydrolysis of the sn-2 position of glycerophospholipids to yield fatty acids and lysophospholipids. Fatty Acids 107-118 phospholipase A2, group IB, pancreas Mus musculus 20-26 18564366-1 2008 Phospholipase A(2) (PLA(2)) enzymes encompass a superfamily of at least 13 extracellular and intracellular esterases that hydrolyze the sn-2 fatty acyl bonds of phospholipids to yield fatty acids and lysophospholipids. Fatty Acids 184-195 phospholipase A2, group IB, pancreas Mus musculus 0-18 20938441-2 2011 Previous studies have shown that Pla2g1b inactivation decreases post-prandial lysophospholipid absorption, and as a consequence increases hepatic fatty acid oxidation and protects against diet-induced obesity and glucose intolerance in mice. Fatty Acids 146-156 phospholipase A2, group IB, pancreas Mus musculus 33-40 21445663-1 2011 Phospholipase A(2) (PLA(2)) is a group of enzymes that hydrolyze the sn-2 position of glycerophospholipids to yield fatty acids and lysophospholipids. Fatty Acids 116-127 phospholipase A2, group IB, pancreas Mus musculus 0-18 21445663-1 2011 Phospholipase A(2) (PLA(2)) is a group of enzymes that hydrolyze the sn-2 position of glycerophospholipids to yield fatty acids and lysophospholipids. Fatty Acids 116-127 phospholipase A2, group IB, pancreas Mus musculus 20-26 18564366-1 2008 Phospholipase A(2) (PLA(2)) enzymes encompass a superfamily of at least 13 extracellular and intracellular esterases that hydrolyze the sn-2 fatty acyl bonds of phospholipids to yield fatty acids and lysophospholipids. Fatty Acids 184-195 phospholipase A2, group IB, pancreas Mus musculus 20-26 14577330-0 2003 [Involvement of phospholipase A2 in the supply of fatty acids required for cholesterol esterification associated with uptake of oxidized low-density lipoprotein in macrophages]. Fatty Acids 50-61 phospholipase A2, group IB, pancreas Mus musculus 16-32 12777475-0 2003 Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification. Fatty Acids 50-61 phospholipase A2, group IB, pancreas Mus musculus 23-39 14577330-3 2003 Our recent studies were undertaken to examine the possible involvement of phospholipase A2 (PLA2) in the supply of fatty acids required for the cholesterol esterification. Fatty Acids 115-126 phospholipase A2, group IB, pancreas Mus musculus 74-90 14577330-3 2003 Our recent studies were undertaken to examine the possible involvement of phospholipase A2 (PLA2) in the supply of fatty acids required for the cholesterol esterification. Fatty Acids 115-126 phospholipase A2, group IB, pancreas Mus musculus 92-96