PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26363927-4	2015	The fat-1 mice express fatty acid n-3 desaturase and produce endogenous n-3 PUFA.	Fatty Acids	23-33	FAT atypical cadherin 1	Mus musculus	4-9	
28900676-5	2017	Because fat-1 Tg+ mice, in which n-6 is endogenously converted into n-3 FAs, contain high n-3 FA levels, they could be a good animal model for studying the effects of n-3 FAs in vivo.	Fatty Acids	72-75	FAT atypical cadherin 1	Mus musculus	8-13	
28972610-9	2017	The gene and protein expression levels involved in fatty acid synthesis and the toll-like receptor (TLR)-4 signaling pathway were significantly inhibited in the fat-1 groups compared with the wild-type groups.	Fatty Acids	51-61	FAT atypical cadherin 1	Mus musculus	161-166	
28972610-10	2017	The endogenously synthesized n-3 PUFAs of the three fat-1 groups, which inhibit fatty acid synthesis and the TLR-4 signaling pathway, prevent HFS diet-induced NAFLD.	Fatty Acids	80-90	FAT atypical cadherin 1	Mus musculus	52-57	
20725110-0	2010	Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids.	Fatty Acids	25-35	FAT atypical cadherin 1	Mus musculus	0-5	
20725110-3	2010	The objective of this study was to use the fat-1 mouse, a transgenic model that synthesizes n-3 from n-6 PUFA, to determine if the fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids, and if so, whether the fatty acid levels would correlate with bone mineral density (BMD) at both skeletal sites.	Fatty Acids	156-166	FAT atypical cadherin 1	Mus musculus	131-136	
20725110-9	2010	Overall, the fat-1 gene resulted in changes in the fatty acid composition of both femoral and vertebral phospholipids.	Fatty Acids	51-61	FAT atypical cadherin 1	Mus musculus	13-18	
19023138-3	2009	Fatty acid profiles of rod outer segments (ROS), cerebellum, plasma, and liver demonstrated significantly lower n-6/n-3 ratios and higher docosahexaenoic acid (DHA) levels in fat-1-SFO compared with wt-SFO.	Fatty Acids	0-10	FAT atypical cadherin 1	Mus musculus	175-180	
31673534-7	2019	Unlike all other mammals, fat-1 transgenic mice ubiquitously express an n-3 fatty acid desaturase, which converts n-6 to n-3 PUFAs, leading to increased n-3 and decreased n-6 PUFA tissue contents.	Fatty Acids	76-86	FAT atypical cadherin 1	Mus musculus	26-31	
23492103-6	2014	Restoration of hepatic omega-3 content in transgenic fat-1 mice expressing an omega-3 desaturase, which allows the endogenous conversion of omega-6 into omega-3 fatty acids, produced a significant reduction in hepatic insulin resistance, steatosis, macrophage infiltration, necroinflammation and lipid peroxidation, accompanied by attenuated expression of genes involved in inflammation, fatty acid uptake and lipogenesis.	Fatty Acids	161-171	FAT atypical cadherin 1	Mus musculus	53-58	
23994161-0	2013	Endogenous synthesis of n-3 PUFA modifies fatty acid composition of kidney phospholipids and eicosanoid levels in the fat-1 mouse.	Fatty Acids	42-52	FAT atypical cadherin 1	Mus musculus	118-123	
20856881-9	2010	These results indicate that the fatty acid changes in fat-1 liver mitochondria may at least partially oppose oxidative stress by limiting ROS production from ETC complex I.	Fatty Acids	32-42	FAT atypical cadherin 1	Mus musculus	54-59	
18977126-9	2008	We conclude that fat-1-containing CD4+ T-cells express a physiologically relevant, n-3 PUFA enriched, membrane fatty acid composition which is resistant to conventional cell culture-induced depletion.	Fatty Acids	111-121	FAT atypical cadherin 1	Mus musculus	17-22