PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9893938-4 1998 Fatty acids increase transcription through peroxisomal proliferator regulatory element (PPRE), to which peroxisome proliferator activated receptor (PPAR) can bind. Fatty Acids 0-11 peroxisome proliferator activated receptor alpha Gallus gallus 104-146 20087658-1 2010 Peroxisome proliferator-activated receptor alpha (PPARA) is involved in fatty acid oxidation by upregulating the expression of acyl-coenzyme A oxidase and carnitine palmitoyltransferase. Fatty Acids 72-82 peroxisome proliferator activated receptor alpha Gallus gallus 0-48 20087658-1 2010 Peroxisome proliferator-activated receptor alpha (PPARA) is involved in fatty acid oxidation by upregulating the expression of acyl-coenzyme A oxidase and carnitine palmitoyltransferase. Fatty Acids 72-82 peroxisome proliferator activated receptor alpha Gallus gallus 50-55 9893938-4 1998 Fatty acids increase transcription through peroxisomal proliferator regulatory element (PPRE), to which peroxisome proliferator activated receptor (PPAR) can bind. Fatty Acids 0-11 peroxisome proliferator activated receptor alpha Gallus gallus 148-152 34741341-9 2021 Dietary MF enhanced fatty acid beta-oxidation in the liver via up-regulating the mRNA expressions of PPARalpha and CPT-I (p < 0.05). Fatty Acids 20-30 peroxisome proliferator activated receptor alpha Gallus gallus 101-110 26031853-0 2016 Role of peroxisome proliferator-activated receptor alpha in the expression of hepatic fatty acid oxidation-related genes in chickens. Fatty Acids 86-96 peroxisome proliferator activated receptor alpha Gallus gallus 8-56 29792171-5 2018 At each stage, 521, 141, 882, 979 and 169 differentially expressed genes were found by the digital gene expression, respectively, which were significantly enriched in the metabolic, PPAR signaling and fatty acid metabolism pathways. Fatty Acids 201-211 peroxisome proliferator activated receptor alpha Gallus gallus 182-186 33901680-6 2021 Down-regulated DEGs and DAPs mainly enriched in pathways related to fatty acid metabolism, fatty acid biosynthesis, and PPAR signaling, and interestingly, up-regulated DEGs and DAPs enriched both in lysosome pathway. Fatty Acids 68-78 peroxisome proliferator activated receptor alpha Gallus gallus 120-124 33901680-6 2021 Down-regulated DEGs and DAPs mainly enriched in pathways related to fatty acid metabolism, fatty acid biosynthesis, and PPAR signaling, and interestingly, up-regulated DEGs and DAPs enriched both in lysosome pathway. Fatty Acids 91-101 peroxisome proliferator activated receptor alpha Gallus gallus 120-124 33407101-7 2021 Based on pathway enrichment analysis, we found expression of genes related to lipogenesis and oxygenolysis (e.g., PPAR signaling pathway, fatty acid biosynthesis, and fatty acid elongation) to be up-regulated with associated down-regulated DNA methylation. Fatty Acids 138-148 peroxisome proliferator activated receptor alpha Gallus gallus 114-118 33407101-7 2021 Based on pathway enrichment analysis, we found expression of genes related to lipogenesis and oxygenolysis (e.g., PPAR signaling pathway, fatty acid biosynthesis, and fatty acid elongation) to be up-regulated with associated down-regulated DNA methylation. Fatty Acids 167-177 peroxisome proliferator activated receptor alpha Gallus gallus 114-118 29939074-10 2018 Genes involved in fatty acid oxidation or carbohydrate utilisation were significantly up- or downregulated (P < 0.05 or P < 0.01), including those involved with highly enriched pathways of lipid metabolism (PPAR, Wnt pathway and inositol phosphate metabolism), cell junctions (focal adhesion and regulation of actin cytoskeleton) and muscle contraction. Fatty Acids 18-28 peroxisome proliferator activated receptor alpha Gallus gallus 213-217 26808997-9 2016 Many other differentially expressed genes were associated with metabolic pathways (including "Fatty acid metabolism", "Alanine, aspartate, and glutamate metabolism", and "Biosynthesis of unsaturated fatty acids") and cell signaling pathways (including "PPAR signaling pathway", "Adipocytokine signaling pathway", "TGF-beta signaling pathway", "MAPK signaling pathway", and "p53 signaling pathway"). Fatty Acids 94-104 peroxisome proliferator activated receptor alpha Gallus gallus 253-257 26031853-4 2016 The aim of the present study was to investigate the regulatory mechanisms of PPARalpha-induced gene expression involved in hepatic fatty acid oxidation in chickens in vivo and in vitro. Fatty Acids 131-141 peroxisome proliferator activated receptor alpha Gallus gallus 77-86 26031853-8 2016 These results suggest that, unlike in mammals, CPT1a and ACO might play an important role in PPARalpha-induced fatty acid oxidation in the liver of chickens. Fatty Acids 111-121 peroxisome proliferator activated receptor alpha Gallus gallus 93-102 26693219-1 2015 PPARalpha agonist clofibrate reduces cholesterol and fatty acid concentrations in rodent liver by an inhibition of SREBP-dependent gene expression. Fatty Acids 53-63 peroxisome proliferator activated receptor alpha Gallus gallus 0-9