PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33469977-1	2021	We investigate binding of linoleate and other potential ligands to the recently discovered fatty acid binding site in the SARS-CoV-2 spike protein, using docking and molecular dynamics simulations.	Fatty Acids	91-101	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	133-138	
33872570-9	2021	Molecular docking studies suggested that pelargonidin binds a fatty acid binding pocket on the receptor binding domain of SARS-CoV-2 Spike protein.	Fatty Acids	62-72	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	133-138	
33469977-6	2021	The SARS-CoV-2 spike fatty acid site may bind a diverse array of ligands, including dietary components, and therefore provides a promising target for therapeutics or prophylaxis.	Fatty Acids	21-31	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	15-20	
34934478-0	2021	The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour.	Fatty Acids	4-14	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	70-75	
32958580-0	2020	Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.	Fatty Acids	5-15	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	69-74	
34934478-0	2021	The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour.	Fatty Acids	4-14	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	98-103	
34934478-2	2021	Recently, a fatty acid binding site was identified in the spike (Toelzer et al.	Fatty Acids	12-22	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	58-63	
34934478-5	2021	Here, dynamical-nonequilibrium molecular dynamics simulations reveal that this fatty acid site is coupled to functionally relevant regions of the spike, some of them far from the fatty acid binding pocket.	Fatty Acids	79-89	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	146-151	
34934478-5	2021	Here, dynamical-nonequilibrium molecular dynamics simulations reveal that this fatty acid site is coupled to functionally relevant regions of the spike, some of them far from the fatty acid binding pocket.	Fatty Acids	179-189	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	146-151	
34934478-6	2021	Removal of a ligand from the fatty acid binding site significantly affects the dynamics of distant, functionally important regions of the spike, including the receptor-binding motif, furin cleavage site and fusion-peptide-adjacent regions.	Fatty Acids	29-39	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	138-143	
35602928-5	2022	This reveals multiple membrane binding sites in the closed spike head that together prefer convex membranes and are modulated by pH, fatty acids and post-translational modifications including glycosylation.	Fatty Acids	133-144	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	59-64	
35039570-3	2022	The objective of this study is to investigate the effect of temperature, fatty acids, ions, and protein concentration on the binding behavior and rates of association and dissociation between the S protein and RBD of SARS-CoV-2 and the hydrophobic aminopropylsilane (APS) biosensors using biolayer interferometry (BLI) validated with molecular dynamics simulation.	Fatty Acids	73-84	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	196-197	
35039570-4	2022	Our results suggest three conditions-high ionic concentration, presence of hydrophobic fatty acids, and low temperature-favor the attachment of S protein and RBD to hydrophobic surfaces.	Fatty Acids	87-98	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	144-145