PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29311449-6 2017 Here we further examined the effect and mechanism of SDG combined with P311 on TGF-beta1-mediated EMT in a rat model of unilateral ureteral occlusion (UUO) renal fibrosis. secoisolariciresinol diglucoside 53-56 transforming growth factor, beta 1 Rattus norvegicus 79-88 29311449-10 2017 Treatment with SDG and P311 improved renal function and histopathological abnormalities, as well as reversing the changes of EMT markers and EMT-related molecules, which indicated SDG combined with P311 could attenuate renal fibrosis in UUO rats, and the underlying mechanism might involve TGF-beta1-mediated EMT and the TGF-beta1-Smad-ILK signaling pathway. secoisolariciresinol diglucoside 15-18 transforming growth factor, beta 1 Rattus norvegicus 290-299 29311449-10 2017 Treatment with SDG and P311 improved renal function and histopathological abnormalities, as well as reversing the changes of EMT markers and EMT-related molecules, which indicated SDG combined with P311 could attenuate renal fibrosis in UUO rats, and the underlying mechanism might involve TGF-beta1-mediated EMT and the TGF-beta1-Smad-ILK signaling pathway. secoisolariciresinol diglucoside 15-18 transforming growth factor, beta 1 Rattus norvegicus 321-330 29311449-10 2017 Treatment with SDG and P311 improved renal function and histopathological abnormalities, as well as reversing the changes of EMT markers and EMT-related molecules, which indicated SDG combined with P311 could attenuate renal fibrosis in UUO rats, and the underlying mechanism might involve TGF-beta1-mediated EMT and the TGF-beta1-Smad-ILK signaling pathway. secoisolariciresinol diglucoside 180-183 transforming growth factor, beta 1 Rattus norvegicus 290-299 29311449-10 2017 Treatment with SDG and P311 improved renal function and histopathological abnormalities, as well as reversing the changes of EMT markers and EMT-related molecules, which indicated SDG combined with P311 could attenuate renal fibrosis in UUO rats, and the underlying mechanism might involve TGF-beta1-mediated EMT and the TGF-beta1-Smad-ILK signaling pathway. secoisolariciresinol diglucoside 180-183 transforming growth factor, beta 1 Rattus norvegicus 321-330