PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34314061-8	2021	VGLL4 knockdown attenuated CNH-induced PH and pulmonary artery remodeling by blunting signal transducer and activator of transcription 3 (STAT3) signaling; conversely, VGLL4 overexpression exacerbated the development of PH.	1-hydroxy-11-norcadinan-5-en-4-one	27-30	vestigial like family member 4	Mus musculus	0-5	
34314061-9	2021	CNH enhanced the acetylation of VGLL4 and increased the interaction of ac-H3K9/VGLL4 and ac-H3K9/STAT3 in the lung tissues, and levels of ac-H3K9, p-STAT3/STAT3, and proliferation-associated protein levels were markedly up-regulated, whereas apoptosis-related protein levels were significantly downregulated, in the lung tissues of mice with CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	0-3	vestigial like family member 4	Mus musculus	32-37	
34314061-9	2021	CNH enhanced the acetylation of VGLL4 and increased the interaction of ac-H3K9/VGLL4 and ac-H3K9/STAT3 in the lung tissues, and levels of ac-H3K9, p-STAT3/STAT3, and proliferation-associated protein levels were markedly up-regulated, whereas apoptosis-related protein levels were significantly downregulated, in the lung tissues of mice with CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	0-3	vestigial like family member 4	Mus musculus	79-84	
34314061-9	2021	CNH enhanced the acetylation of VGLL4 and increased the interaction of ac-H3K9/VGLL4 and ac-H3K9/STAT3 in the lung tissues, and levels of ac-H3K9, p-STAT3/STAT3, and proliferation-associated protein levels were markedly up-regulated, whereas apoptosis-related protein levels were significantly downregulated, in the lung tissues of mice with CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	342-345	vestigial like family member 4	Mus musculus	32-37	
34314061-9	2021	CNH enhanced the acetylation of VGLL4 and increased the interaction of ac-H3K9/VGLL4 and ac-H3K9/STAT3 in the lung tissues, and levels of ac-H3K9, p-STAT3/STAT3, and proliferation-associated protein levels were markedly up-regulated, whereas apoptosis-related protein levels were significantly downregulated, in the lung tissues of mice with CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	342-345	vestigial like family member 4	Mus musculus	79-84	
34314061-10	2021	Notably, abrogation of VGLL4 acetylation reversed CNH-induced PH and pulmonary artery remodeling and suppressed STAT3 signaling.	1-hydroxy-11-norcadinan-5-en-4-one	50-53	vestigial like family member 4	Mus musculus	23-28	
34314061-12	2021	In conclusion, VGLL4 acetylation upregulation could contribute to CNH-induced PH and pulmonary artery remodeling via STAT3 signaling, and abrogation of VGLL4 acetylation reversed CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	66-69	vestigial like family member 4	Mus musculus	15-20	
34314061-12	2021	In conclusion, VGLL4 acetylation upregulation could contribute to CNH-induced PH and pulmonary artery remodeling via STAT3 signaling, and abrogation of VGLL4 acetylation reversed CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	179-182	vestigial like family member 4	Mus musculus	15-20	
34314061-12	2021	In conclusion, VGLL4 acetylation upregulation could contribute to CNH-induced PH and pulmonary artery remodeling via STAT3 signaling, and abrogation of VGLL4 acetylation reversed CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	179-182	vestigial like family member 4	Mus musculus	152-157	
34314061-13	2021	Pharmacological or genetic deletion of VGLL4 might be a potential target for therapeutic interventions in CNH-induced PH.	1-hydroxy-11-norcadinan-5-en-4-one	106-109	vestigial like family member 4	Mus musculus	39-44