PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23856460-8 2013 Orteronel at 15mg/kg/day (7.5mg/kg/treatment, twice daily [bid]) continued to suppress the estradiol surge prior to the start of luteal phase for 1.5-times the average duration of three consecutive, pre-treatment menstrual cycles, while serum progesterone was maintained at levels almost equal to those in the luteal phase although a certain portion of this increased level of progesterone could be of adrenal-origin. orteronel 0-9 BH3 interacting domain death agonist Rattus norvegicus 59-62