PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21872575-11 2011 Furthermore, p53 siRNA and p21 siRNA transfection attenuated adriamycin-induced SA-beta-gal staining. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid 80-91 H3 histone pseudogene 16 Homo sapiens 27-30 20647331-8 2010 The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid 247-258 H3 histone pseudogene 16 Homo sapiens 166-169 23430755-6 2013 By double labeling of senescent cells, first by SA-beta-Gal and then by antibodies against genes related to cellular senescence, we found that p21, p16, and RARbeta, but not p53, were upregulated by bexarotene in mammary tumors and in breast cancer cell lines, suggesting involvement of multiple signaling pathways in mediating the senescence program of rexinoids. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid 48-59 H3 histone pseudogene 16 Homo sapiens 143-146