PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20647331-8	2010	The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	247-258	tumor protein p53	Homo sapiens	22-25	
22090360-9	2012	Expression of disruptive TP53 mutations significantly decreased radiation-induced senescence, as measured by SA-beta-gal staining, p21 expression, and release of ROS.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	109-120	tumor protein p53	Homo sapiens	25-29	
21872575-11	2011	Furthermore, p53 siRNA and p21 siRNA transfection attenuated adriamycin-induced SA-beta-gal staining.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	80-91	tumor protein p53	Homo sapiens	13-16	
23982736-8	2013	In addition, p53 siRNA transfection attenuated metformin-induced SA-beta-gal staining.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	65-76	tumor protein p53	Homo sapiens	13-16	
20647331-8	2010	The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	247-258	tumor protein p53	Homo sapiens	143-146	
19048622-5	2009	The TP53 wild-type tumor showed a strong early induction of senescence-like phenotype with overexpression of SA-beta-gal and p21(CIP1).	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	109-120	tumor protein p53	Homo sapiens	4-8	
15753076-9	2005	Senescence induction, tested as staining for SA-beta-gal, in reoxygenated progenitor cells was closely correlated with extent of DNA damage and phosphorylation of ATM at Ser-1981 and p53 at Ser-15.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	45-56	tumor protein p53	Homo sapiens	183-186	
35468881-5	2022	Following overexpression or silencing of JMJD2C/MDM2/p53/IL5RA, the 50% concentration of inhibition (IC50) and the biological characteristics of MUM-2B and MUM-2B/CDDP cells were examined using CCK-8 assay, SA-beta-gal staining, fluorescence-activated cell sorting analysis, and Transwell assay.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	207-218	tumor protein p53	Homo sapiens	53-56	
35325405-10	2022	The gene expression of p16, p21, and p53 of smumf cells did not change until P10 and SA-beta-gal activity did not increase until P14.	2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid	85-96	tumor protein p53	Homo sapiens	37-40