PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20647331-8 2010 The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid 247-258 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 37-41 20647331-8 2010 The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid 247-258 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 182-186