PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29054429-7	2018	However, pretreatment of MDA-MB-231 cells with SF1670, a PTEN inhibitor, abolished the hydrophobic surface-induced activation of the intrinsic pathway.	SF1670	47-53	phosphatase and tensin homolog	Homo sapiens	57-61	
32964957-0	2020	SF1670 inhibits apoptosis and inflammation via the PTEN/Akt pathway and thus protects intervertebral disc degeneration.	SF1670	0-6	phosphatase and tensin homolog	Homo sapiens	51-55	
32964957-4	2020	In this study, we investigated the protective effect of SF1670, as a specific PTEN inhibitor, on an in vitro NP cells degenerated model.	SF1670	56-62	phosphatase and tensin homolog	Homo sapiens	78-82	
32964957-13	2020	CONCLUSIONS: Overall, these results demonstrated that SF1670 prevented NP degradation via suppressing apoptosis and inflammation through inhibition of PTEN and activation of Akt.	SF1670	54-60	phosphatase and tensin homolog	Homo sapiens	151-155	
30816513-8	2019	Overexpression of p-Akt by transfection with a constitutively active form (caAkt), and the p-PTEN inhibitor SF1670 prevented resveratrol-induced cell death.	SF1670	108-114	phosphatase and tensin homolog	Homo sapiens	93-97	
35451580-10	2022	Whilst, treatment with 10 muM of special inhibitors, including LY294002 (PI3K) or PD098059 (MAPK), increased Rho 123-associated MFI, treatment with 10 muM of SF1670 (PTEN) almost abolished the effect of miR-205 overexpression (P<0.05).	SF1670	158-164	phosphatase and tensin homolog	Homo sapiens	166-170	
32329824-3	2020	The myeloma U266 cells transfected with negative control (NC) were used as control group, those transfected with miR-32 inhibitor as transfection group, and those transfected with miR-32 inhibitor and treated with PTEN inhibitor SF1670 as the transfection + inhibitor group.	SF1670	229-235	phosphatase and tensin homolog	Homo sapiens	214-218	
32329824-9	2020	In addition, the mRNA expression of PTEN in myeloma cells rose after transfection with the miR-32 inhibitor, and declined after addition of the PTEN inhibitor SF1670, which were consistent with the results of Western blotting.	SF1670	159-165	phosphatase and tensin homolog	Homo sapiens	36-40	
32329824-9	2020	In addition, the mRNA expression of PTEN in myeloma cells rose after transfection with the miR-32 inhibitor, and declined after addition of the PTEN inhibitor SF1670, which were consistent with the results of Western blotting.	SF1670	159-165	phosphatase and tensin homolog	Homo sapiens	144-148	
32329824-10	2020	Besides, the proliferation ability of myeloma cells was evidently weakened after transfection with the miR-32 inhibitor, while it was restored to a certain extent after addition of the PTEN inhibitor SF1670.	SF1670	200-206	phosphatase and tensin homolog	Homo sapiens	185-189	
32329824-11	2020	Moreover, the number of apoptotic myeloma cells was remarkably larger after transfection with the miR-32 inhibitor, while it was remarkably smaller after addition of the PTEN inhibitor SF1670.	SF1670	185-191	phosphatase and tensin homolog	Homo sapiens	170-174	
32329824-12	2020	The expressions of pro-apoptotic proteins Bak and caspase-9 in myeloma cells were significantly increased after transfection with the miR-32 inhibitor (p<0.05), and significantly decreased after addition of the PTEN inhibitor SF1670, while the expressions of anti-apoptotic proteins Bcl-2 and survivin were opposite to those of Bak and caspase-9.	SF1670	226-232	phosphatase and tensin homolog	Homo sapiens	211-215	
26701983-8	2016	Finally, blocking PTEN with SF1670 largely diminished the inhibitory effect of 3-DZNeP on renal myofibroblast activation.	SF1670	28-34	phosphatase and tensin homolog	Homo sapiens	18-22	
28766684-6	2017	Pretreatment of PTEN inhibitor SF1670 enhances the PI3K signaling pathway and represses NB4 cell differentiation.	SF1670	31-37	phosphatase and tensin homolog	Homo sapiens	16-20	
24832086-9	2014	Serum effects on IRS-1 were recapitulated by exogenous insulin and the PTEN-specific inhibitor SF1670.	SF1670	95-101	phosphatase and tensin homolog	Homo sapiens	71-75