PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21762526-0	2011	Preventive effect of Ibrolipim on suppressing lipid accumulation and increasing lipoprotein lipase in the kidneys of diet-induced diabetic minipigs.	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	21-30	lipoprotein lipase	Homo sapiens	80-98	
21762526-2	2011	The purpose of this study was to observe the preventive effects of Ibrolipim, a LPL activator, on lipid accumulation and LPL expression in the kidneys of minipigs fed a high-sucrose and high-fat diet (HSFD).	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	67-76	lipoprotein lipase	Homo sapiens	80-83	
21762526-2	2011	The purpose of this study was to observe the preventive effects of Ibrolipim, a LPL activator, on lipid accumulation and LPL expression in the kidneys of minipigs fed a high-sucrose and high-fat diet (HSFD).	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	67-76	lipoprotein lipase	Homo sapiens	121-124	
21762526-9	2011	In contrast, supplementing Ibrolipim into HSFD lowered body weight, plasma glucose, insulin, triglyceride and urinary albumin concentrations while it increased plasma total cholesterol and HDL-C. Ibrolipim suppressed the renal accumulation of triglyceride and cholesterol, and stimulated the diet-induced down-regulation of LPL expression and activity in the kidney.	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	27-36	lipoprotein lipase	Homo sapiens	324-327	
21762526-9	2011	In contrast, supplementing Ibrolipim into HSFD lowered body weight, plasma glucose, insulin, triglyceride and urinary albumin concentrations while it increased plasma total cholesterol and HDL-C. Ibrolipim suppressed the renal accumulation of triglyceride and cholesterol, and stimulated the diet-induced down-regulation of LPL expression and activity in the kidney.	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	196-205	lipoprotein lipase	Homo sapiens	324-327	
21762526-10	2011	CONCLUSIONS: Ibrolipim exerts renoprotective and hypolipidemic effects via the increase in renal LPL activity and expression, and thus the increased expression and activity of renal LPL play a vital role in suppressing renal lipid accumulation and ameliorating proteinuria in diet-induced diabetic minipigs.	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	13-22	lipoprotein lipase	Homo sapiens	97-100