PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15613375-2 2005 Although their transport stoichiometries have not been directly determined, significant cooperativities in the Na+ activation of SMIT1 and SMIT2 suggest that more than one Na+ ion drives the transport of each myo-inositol. Inositol 209-221 solute carrier family 5 member 11 Homo sapiens 139-144 15172003-11 2004 Significantly lower myo-inositol concentrations were observed in mothers with SLC5A11 CC-genotype, mean (SD) 14.2 (2.6)micromol/L compared to SLC5A11 TT-genotype, 17.0 (3.4)micromol/L, P <0.05 . Inositol 20-32 solute carrier family 5 member 11 Homo sapiens 78-85 15172003-11 2004 Significantly lower myo-inositol concentrations were observed in mothers with SLC5A11 CC-genotype, mean (SD) 14.2 (2.6)micromol/L compared to SLC5A11 TT-genotype, 17.0 (3.4)micromol/L, P <0.05 . Inositol 20-32 solute carrier family 5 member 11 Homo sapiens 142-149 15172003-15 2004 Moreover, maternal SLC5A11 544C > T polymorphism contributes to the serum myo-inositol concentration. Inositol 74-86 solute carrier family 5 member 11 Homo sapiens 19-26 28283543-3 2017 Here, we discovered that KCNQ2/3 channels isoform-specifically colocalize with SMIT1 and SMIT2 at sciatic nerve nodes of Ranvier and in axon initial segments, and form channel-transporter complexes in vitro and in vivo KCNQ2/3 coexpression protected SMIT1 activity from the otherwise inhibitory effects of cellular depolarization imposed by elevating extracellular [K+], and KCNQ2 was required for potentiation of SMIT activity by myo-inositol preincubation. Inositol 431-443 solute carrier family 5 member 11 Homo sapiens 89-94 30161013-4 2018 Human SGLT6 is an active transporter of myo-inositol and D-glucose. Inositol 40-52 solute carrier family 5 member 11 Homo sapiens 6-11 19032932-0 2009 Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells. Inositol 57-66 solute carrier family 5 member 11 Homo sapiens 6-37 26352407-8 2015 In contrast, for the SLC5A11 locus, we found increased levels of myo-inositol in urine whereas mGWAS in blood reported decreased levels for the same genetic variant. Inositol 65-77 solute carrier family 5 member 11 Homo sapiens 21-28 19032932-8 2009 Therefore, expression and/or function of SMIT2, a high affinity transporter specific for DCI and myo-inositol, may be reduced in diabetes mellitus, insulin resistance and polycystic ovary syndrome causing the abnormal DCI metabolism observed in these conditions. Inositol 97-109 solute carrier family 5 member 11 Homo sapiens 41-46 19032932-0 2009 Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells. Inositol 57-66 solute carrier family 5 member 11 Homo sapiens 39-44 19032932-1 2009 To characterize the function of the sodium/inositol symporter SMIT2 in skeletal muscle, human SMIT2 cDNA was transfected into L6 myoblasts using pcDNA3.1 expression vector. Inositol 43-51 solute carrier family 5 member 11 Homo sapiens 62-67