PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7623608-2 1995 Myo-inositol incorporation into HSF was dependent on an active transport system via Na(+)-K+ ATPase activity based on the results with Na+ deprivation and ouabain (5 mM). Inositol 0-12 interleukin 6 Homo sapiens 32-35 27658890-8 2016 Compared with placebo, myo-inositol intervention significantly reduced IL6 levels in BAL over 6 months (P = 0.03). Inositol 23-35 interleukin 6 Homo sapiens 71-74 17130674-5 2006 2-APB [(2-aminoethoxy)diphenylborane], an inositol 1,4,5-trisphosphate (IP(3))-receptor antagonist, inhibited UTP-induced IL-6 mRNA expression; and the action of A23187, a Ca(2+) ionophore, resembled the action of UTP. Inositol 42-50 interleukin 6 Homo sapiens 122-126 7623608-1 1995 The effects of elevated glucose and eicosapentaenoic acid (EPA, C20:5 omega 3) on myo-inositol uptake in human skin fibroblasts (HSF) were evaluated. Inositol 82-94 interleukin 6 Homo sapiens 129-132 32049375-7 2020 The MCI/MI- or MI- induced secretion of IL-1beta, TNF and IL-6 by PBMC was analysed by flow cytometry. Inositol 8-10 interleukin 6 Homo sapiens 58-62 32049375-7 2020 The MCI/MI- or MI- induced secretion of IL-1beta, TNF and IL-6 by PBMC was analysed by flow cytometry. Inositol 15-17 interleukin 6 Homo sapiens 58-62 32271462-7 2020 Myo-Inositol proved to reduce IL-6 levels in a number of conditions and to mitigate the inflammatory cascade, while being devoid of any significant side effects. Inositol 0-12 interleukin 6 Homo sapiens 30-34 33254564-0 2020 Role of inositol to improve surfactant functions and reduce IL-6 levels: A potential adjuvant strategy for SARS-CoV-2 pneumonia? Inositol 8-16 interleukin 6 Homo sapiens 60-64 33493945-10 2021 Myo-inositol down-regulates the expression of IL-6 by phosphatidyl-inositol-3-kinase (PI3K) pathway. Inositol 0-12 interleukin 6 Homo sapiens 46-50 33254564-5 2020 In addition, myo-inositol has been found able to decrease the levels of IL-6 in several experimental settings, due to an effect on the inositol-requiring enzyme 1 (IRE1)-X-box-binding protein 1 (XBP1) and on the signal transducer and activator of transcription 3 (STAT3) pathways. Inositol 13-25 interleukin 6 Homo sapiens 72-76 33254564-6 2020 In this scenario, treatment with myo-inositol may be able to reduce IL-6 dependent inflammatory response and improve oxygenation in patients with severe ARDS by SARS-CoV-2. Inositol 33-45 interleukin 6 Homo sapiens 68-72