PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11483660-4 2001 Addition of inositol or 8-Br-cyclic GMP completely reversed these Abeta-induced changes. Inositol 12-20 amyloid beta precursor protein Rattus norvegicus 66-71 11483660-8 2001 Addition of inositol or 8-Br-cyclic GMP prevented the effect of Abeta-treatment on the neurotoxicity of glutamate. Inositol 12-20 amyloid beta precursor protein Rattus norvegicus 64-69 16723396-8 2006 NMR spectrum analysis of the animals cerebrospinal fluid revealed a strong reduction trend in several metabolites in Abeta-infused rats, including lactate and myo-inositol, supporting the idea of dysfunctional astrocytes. Inositol 159-171 amyloid beta precursor protein Rattus norvegicus 117-122 10764800-0 2000 Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity. Inositol 0-8 amyloid beta precursor protein Rattus norvegicus 103-108 10764800-4 2000 The ability of inositol stereoisomers to interact with and stabilize small Abeta complexes was addressed. Inositol 15-23 amyloid beta precursor protein Rattus norvegicus 75-80 10764800-8 2000 We demonstrate that inositol-Abeta interactions result in a complex that is non-toxic to nerve growth factor-differentiated PC-12 cells and primary human neuronal cultures. Inositol 20-28 amyloid beta precursor protein Rattus norvegicus 29-34 10764800-10 2000 The use of inositol stereoisomers allowed us to elucidate an important structure-activity relationship between Abeta and inositol. Inositol 11-19 amyloid beta precursor protein Rattus norvegicus 111-116 10764800-10 2000 The use of inositol stereoisomers allowed us to elucidate an important structure-activity relationship between Abeta and inositol. Inositol 121-129 amyloid beta precursor protein Rattus norvegicus 111-116