PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31298405-1	2019	OBJECTIVE: The aim of this clinical trial was to evaluate the efficacy of seven different ratios between two inositols stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), in the therapy of polycystic ovary syndrome (PCOS).	Inositol	156-172	enoyl-CoA delta isomerase 1	Homo sapiens	174-177	
31298405-5	2019	RESULTS: We found that the 40:1 MI/DCI ratio is the best for PCOS therapy aimed at restoring ovulation and normalizing important parameters in these patients.	Inositol	32-34	enoyl-CoA delta isomerase 1	Homo sapiens	35-38	
31298405-8	2019	CONCLUSIONS: Our data demonstrated that DCI activity is beneficial mainly at a specific ratio with MI, whereas the increase of DCI causes the loss of the beneficial effects at reproductive level.	Inositol	99-101	enoyl-CoA delta isomerase 1	Homo sapiens	40-43	
25268566-2	2015	The effectiveness of D-chiro-inositol (DCI) treatment in improving insulin resistance in PCOS patients has been confirmed in several reports.	Inositol	21-37	enoyl-CoA delta isomerase 1	Homo sapiens	39-42	
26927948-4	2016	Inositol is a polyalcohol, naturally occurring as nine stereoisomers, including D-chiro-inositol (DCI) and myo-inositol (MI), which have prominent roles in the metabolism of glucose and free fatty acids.	Inositol	0-8	enoyl-CoA delta isomerase 1	Homo sapiens	98-101	
26927948-4	2016	Inositol is a polyalcohol, naturally occurring as nine stereoisomers, including D-chiro-inositol (DCI) and myo-inositol (MI), which have prominent roles in the metabolism of glucose and free fatty acids.	Inositol	80-96	enoyl-CoA delta isomerase 1	Homo sapiens	98-101	
19032932-5	2009	The K(m) of DCI and myo-inositol for DCI uptake was 111.0 and 158.0 microM, respectively, whereas glucose competed for DCI uptake with a K(i) of 6.1 mM.	Inositol	20-32	enoyl-CoA delta isomerase 1	Homo sapiens	37-40	
19032932-5	2009	The K(m) of DCI and myo-inositol for DCI uptake was 111.0 and 158.0 microM, respectively, whereas glucose competed for DCI uptake with a K(i) of 6.1 mM.	Inositol	20-32	enoyl-CoA delta isomerase 1	Homo sapiens	37-40	
34439531-7	2021	In addition, other natural molecules, myo-inositol (MI) and d-chiro-inositol (DCI), ameliorate sperm quality.	Inositol	60-76	enoyl-CoA delta isomerase 1	Homo sapiens	78-81	
19059532-1	2009	We have previously shown that women with polycystic ovary syndrome (PCOS) have increased urinary clearance of D-chiro-inositol (uCl(DCI)), which was positively associated with hyperinsulinemia.	Inositol	110-126	enoyl-CoA delta isomerase 1	Homo sapiens	132-135	
19059532-8	2009	In this group, plasma DCI was increased by 3-fold (P = .02), with a 3-fold decrease in the uCl(DCI) to urinary clearance of myo-inositol ratio, which was almost significant (P = .07).	Inositol	124-136	enoyl-CoA delta isomerase 1	Homo sapiens	95-98	
34680494-1	2021	D-chiro-inositol (DCI) is a natural compound detectable in cell membranes, which is highly conserved as a biological signaling molecule.	Inositol	0-16	enoyl-CoA delta isomerase 1	Homo sapiens	18-21