PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27436854-1 2017 The ribonuclease angiogenin is a component of the mammalian stress response that is secreted by renal epithelial cells on activation of the inositol-requiring enzyme 1alpha (IRE1alpha)-active spliced X-box binding protein 1 (sXBP1) axis and instrumental to the adaptation to AKI associated with endoplasmic reticulum stress. Inositol 140-148 angiogenin Homo sapiens 17-27 2457905-0 1988 Angiogenin activates endothelial cell phospholipase C. Low concentrations of angiogenin activate the inositol-specific phospholipase C of cultured pulmonary artery, umbilical vein, and capillary endothelial cells, promoting a transient increase in the intracellular levels of 1,2-diacylglycerol and inositol trisphosphate. Inositol 101-109 angiogenin Homo sapiens 0-10 2457905-0 1988 Angiogenin activates endothelial cell phospholipase C. Low concentrations of angiogenin activate the inositol-specific phospholipase C of cultured pulmonary artery, umbilical vein, and capillary endothelial cells, promoting a transient increase in the intracellular levels of 1,2-diacylglycerol and inositol trisphosphate. Inositol 101-109 angiogenin Homo sapiens 77-87 26823555-5 2016 In cultured renal epithelial cells, ER stress specifically induced angiogenin secretion under the selective control of inositol-requiring enzyme 1alpha, a key activator of the unfolded protein response. Inositol 119-127 angiogenin Homo sapiens 67-77 26823555-6 2016 The transcription factors spliced X-box-binding protein 1 and p65, which are activated by inositol-requiring enzyme 1alpha upon ER stress, each bound the angiogenin promoter and controlled the amount of angiogenin secreted. Inositol 90-98 angiogenin Homo sapiens 154-164 26823555-6 2016 The transcription factors spliced X-box-binding protein 1 and p65, which are activated by inositol-requiring enzyme 1alpha upon ER stress, each bound the angiogenin promoter and controlled the amount of angiogenin secreted. Inositol 90-98 angiogenin Homo sapiens 203-213 27279487-2 2016 We have previously shown that inositol 1,4,5-trisphosphate receptor-binding protein released with inositol 1,4,5-trisphosphate (IRBIT) mediates ANG II-induced exocytosis of NHE3 in cultured proximal tubule epithelial cells. Inositol 30-38 angiogenin Homo sapiens 144-147 19185362-9 2010 Upon multivariate analysis, methotrexate use (p=0.006) and prior mycocardial infarction (MI) (p=0.034) were associated with higher angiogenin levels; body mass index (BMI) (p=0.034) and presence of RD (p=0.029) itself predicted lower levels. Inositol 89-91 angiogenin Homo sapiens 131-141