PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30783947-1 2019 We recently characterized the cytotoxic action of a novel phenformin derivative, 2-(2-chlorophenyl)ethylbiguanide (2-Cl-Phen), on HT-29 cells under a serum- and glucose-deprived condition and found that 2-Cl-Phen attenuated ATF4 and GRP78, typical downstream targets of the unfolded protein response (UPR), together with c-Myc protein expression in a transcriptional and posttranscriptional manner. Phenformin 58-68 activating transcription factor 4 Homo sapiens 224-228