PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22858590-4 2012 Single-turnover kinetics of NEIL1 revealed that removal of 5-hydroxycytosine (5-OHC) and 5-hydroxyuracil (5-OHU) is ~25 and ~10-fold faster in duplex DNA compared to single-stranded DNA, respectively, and also faster than removal of dihydrothymine (DHT) and dihydrouracil (DHU), both in double-stranded and single-stranded DNA. 5-ohc 78-83 nei like DNA glycosylase 1 Homo sapiens 28-33 18543945-4 2008 Most notably, quantitative examination of the substrate specificity with hNEIL1 revealed that the hydantoin lesions are excised much more efficiently (>100-fold faster) than the reported standard substrates thymine glycol (Tg) and 5-hydroxycytosine (5-OHC). 5-ohc 253-258 nei like DNA glycosylase 1 Homo sapiens 73-79