PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3131117-12 1988 The effect of TMB-8 suggests that release of a small intracellular calcium pool may mediate the early actions of PRL in Nb2 cells. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 14-19 prolactin Rattus norvegicus 113-116 7753765-3 1995 Exposure of GH3 cells to the inhibitor of intracellular Ca2+ mobilization, 8-(diethylamino)-octyl 3,4,5-trimethoxybenzoate hydrochloride (TMB-8) prevented the prolactin-releasing effect of remoxipride whereas pretreatment with the membrane Ca2+ channel antagonist nimodipine did not influence the response. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 138-143 prolactin Rattus norvegicus 159-168 3683076-0 1987 The intracellular calcium antagonist, TMB-8, inhibits prolactin gene expression in GH3 cells. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 38-43 prolactin Rattus norvegicus 54-63 3683076-1 1987 We examined the effects of the drug, TMB-8, which promotes sequestration of intracellular Ca2+, on the ability of extracellular Ca2+ to stimulate prolactin gene expression in GH3 cells. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 37-42 prolactin Rattus norvegicus 146-155 3683076-2 1987 TMB-8 inhibited prolactin mRNA levels in a dose-dependent manner in the concentration range of 2.5-10 microM. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 0-5 prolactin Rattus norvegicus 16-25 3683076-6 1987 Both TMB-8 and the calmodulin inhibitor, calmidazolium, reversed the effects of Ca2+ on prolactin mRNA levels in cells that had been pretreated for 2 days with 0.4 mM CaCl2. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate 5-10 prolactin Rattus norvegicus 88-97