PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27974594-7	2017	Macrophage depletion reversed C5a agonist peptide-induced TNF-alpha up-regulation and APN down-regulation in the PVAT of DOCA mice.	Desoxycorticosterone Acetate	121-125	hemolytic complement	Mus musculus	30-33	
25573852-6	2015	Furthermore, we identified the complement 5a (C5a) as the major C3 activation product that was involved in macrophage polarization and DOCA-salt-induced vascular injury.	Desoxycorticosterone Acetate	135-139	hemolytic complement	Mus musculus	46-49	
25573852-8	2015	CONCLUSIONS: The presence and activation of bone marrow-derived macrophages in PVAT are crucial for complement activation in hypertensive vascular inflammation, and C5a plays a critical role in DOCA-salt-induced vascular injury by stimulating macrophage polarization toward a proinflammatory M1 phenotype in PVAT.	Desoxycorticosterone Acetate	194-198	hemolytic complement	Mus musculus	165-168