PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28658642-4	2017	When the nanomicelles were tested in folate-receptor overexpressing ovarian and cervical cancer cells they exhibited high anticancer activity causing significant cell population to undergo apoptosis due to upregulation of tumor suppressor phosphatase and tensin homolog (PTEN) and inhibition of nuclear factor kappa-B (NFkappaB), which further confirmed the targeting ability and anticancer potentials of folate-targeted formulations.	Folic Acid	37-43	phosphatase and tensin homolog	Homo sapiens	271-275	
26520043-0	2016	Tailored-CuO-nanowire decorated with folic acid mediated coupling of the mitochondrial-ROS generation and miR425-PTEN axis in furnishing potent anti-cancer activity in human triple negative breast carcinoma cells.	Folic Acid	37-47	phosphatase and tensin homolog	Homo sapiens	113-117	
27113042-11	2016	These findings demonstrated that folic acid protected neuronal cells against Al-malt-induced apoptosis by preventing the downregulation of miR-19 and modulation of miR-19 related downstream PTEN/AKT/p53 pathway.	Folic Acid	33-43	phosphatase and tensin homolog	Homo sapiens	190-194	
23219837-0	2013	Folic acid enforces DNA methylation-mediated transcriptional silencing of PTEN, APC and RARbeta2 tumour suppressor genes in breast cancer.	Folic Acid	0-10	phosphatase and tensin homolog	Homo sapiens	74-78	
23219837-3	2013	Using the methylation sensitive restriction analysis (MSRA) and real-time RT-PCR we tested the effect of folic acid on DNA promoter methylation and expression of PTEN, APC and RARbeta2 tumour suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines with different invasive capacity.	Folic Acid	105-115	phosphatase and tensin homolog	Homo sapiens	162-166