PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29777263-13	2018	Hepatic Ppara gene expression was upregulated in female offspring only (1.51-fold, p   0.05) and was restored in the female offspring by folate treatment (p   0.05).	Folic Acid	137-143	peroxisome proliferator activated receptor alpha	Rattus norvegicus	8-13	
27152636-7	2016	Folic acid supplementation in late gestation or throughout pregnancy significantly decreased Er-alpha, Gr and Ppar-alpha gene expression in the liver (P<.05).	Folic Acid	0-10	peroxisome proliferator activated receptor alpha	Rattus norvegicus	110-120	
18186951-2	2008	We investigated the effect of feeding pregnant rats a protein-restricted (PR) diet with different amounts of folic acid on the methylation of individual CpG dinucleotides in the hepatic PPAR alpha promoter in juvenile offspring, and the effect of the maternal PR diet on CpG methylation in adult offspring.	Folic Acid	109-119	peroxisome proliferator activated receptor alpha	Rattus norvegicus	186-196	
32476787-0	2020	Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARalpha.	Folic Acid	0-10	peroxisome proliferator activated receptor alpha	Rattus norvegicus	107-116	
32476787-8	2020	Furthermore, peroxisome proliferator-activated receptor alpha (PPARalpha) and silence information regulation factor 1 (SIRT1) were restored by folic acid in HFD-fed rats and palmitic acid-exposed Huh7 cell line.	Folic Acid	143-153	peroxisome proliferator activated receptor alpha	Rattus norvegicus	13-61	
32476787-8	2020	Furthermore, peroxisome proliferator-activated receptor alpha (PPARalpha) and silence information regulation factor 1 (SIRT1) were restored by folic acid in HFD-fed rats and palmitic acid-exposed Huh7 cell line.	Folic Acid	143-153	peroxisome proliferator activated receptor alpha	Rattus norvegicus	63-72	
21986714-11	2012	Folic acid supplementation of the maternal diet was associated with reduced expression of PPARalpha, PPARgamma, and LXRalpha in the liver (P < 0.001).	Folic Acid	0-10	peroxisome proliferator activated receptor alpha	Rattus norvegicus	90-99	
21986714-17	2012	Furthermore, the expression of LXRalpha, PPARalpha, and PPARgamma in the liver and adipose tissue largely depends on the protein and folic acid content in the maternal diet during gestation.	Folic Acid	133-143	peroxisome proliferator activated receptor alpha	Rattus norvegicus	41-50	
32476787-11	2020	CONCLUSION: Folic acid improves hepatic lipid metabolism by upregulating PPARalpha levels via a SIRT1-dependent mechanism and restores hepatic one-carbon metabolism and diversity of gut microbiota, thereby attenuating HFD-induced NASH in rats.	Folic Acid	12-22	peroxisome proliferator activated receptor alpha	Rattus norvegicus	73-82