PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32796716-6 2020 Its decreased expression plays a prominent role in the heart, liver and brain of rat as manifestations of fetal programming produced by deficit in vitamin B12 and folate during pregnancy and lactation through imbalanced methylation/acetylation of PGC1alpha and altered expression and methylation of nuclear receptors. Folic Acid 163-169 PPARG coactivator 1 alpha Rattus norvegicus 247-256 22459404-1 2013 BACKGROUND: The deficiency in methyl donors, folate and vitamin B12, increases homocysteine and produces myocardium hypertrophy with impaired mitochondrial fatty acid oxidation and increased BNP, through hypomethylation of peroxisome-proliferator-activated-receptor gamma co-activator-1alpha, in rat. Folic Acid 45-51 PPARG coactivator 1 alpha Rattus norvegicus 223-291