PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20925121-10	2012	Confocal laser microscope examination also showed that capsaicin induced the releases of AIF, ATF-4, and GADD153 from mitochondria of SCC-4 cells.	Capsaicin	55-64	DNA damage inducible transcript 3	Homo sapiens	105-112	
21859781-5	2012	Capsaicin treatment triggered ER stress by promoting the production of reactive oxygen species (ROS), increasing levels of inositol-requiring 1 enzyme (IRE1), growth arrest and DNA-damage-inducible 153 (GADD153) and glucose-regulated protein 78 (GRP78).	Capsaicin	0-9	DNA damage inducible transcript 3	Homo sapiens	159-201	
21859781-5	2012	Capsaicin treatment triggered ER stress by promoting the production of reactive oxygen species (ROS), increasing levels of inositol-requiring 1 enzyme (IRE1), growth arrest and DNA-damage-inducible 153 (GADD153) and glucose-regulated protein 78 (GRP78).	Capsaicin	0-9	DNA damage inducible transcript 3	Homo sapiens	203-210	
29339762-7	2018	Capsaicin treatment increased the expression of sXbp1 and Chop in brown preadipocytes and did not enhance lipid accumulation or Ucp1 expression in Xbp1 knockdown cells.	Capsaicin	0-9	DNA damage inducible transcript 3	Homo sapiens	58-62	
23781265-4	2013	Knockdown of growth arrest- and DNA damage-inducible gene 153 (GADD153), a marker of the endoplasmic-reticulum-stress- (ERS-) mediated apoptosis pathway, by specific siRNA attenuated capsaicin-induced apoptosis both in PANC-1 and SW1990 cells.	Capsaicin	183-192	DNA damage inducible transcript 3	Homo sapiens	13-61	
23781265-4	2013	Knockdown of growth arrest- and DNA damage-inducible gene 153 (GADD153), a marker of the endoplasmic-reticulum-stress- (ERS-) mediated apoptosis pathway, by specific siRNA attenuated capsaicin-induced apoptosis both in PANC-1 and SW1990 cells.	Capsaicin	183-192	DNA damage inducible transcript 3	Homo sapiens	63-70	
23781265-6	2013	Furthermore, capsaicin increased the expression of some key ERS markers, including glucose-regulated protein 78 (GRP78), phosphoprotein kinase-like endoplasmic reticulum kinase (phosphoPERK), and phosphoeukaryotic initiation factor-2 alpha (phospho-eIF2 alpha ), activating transcription factor 4 (ATF4) and GADD153 in tumor tissues.	Capsaicin	13-22	DNA damage inducible transcript 3	Homo sapiens	308-315	
19699254-6	2009	Capsaicin treatment triggered ER stress by increasing levels of IRE1, GADD153/Chop, GRP78/Bip, and activated caspase-4.	Capsaicin	0-9	DNA damage inducible transcript 3	Homo sapiens	70-77	
20371669-4	2010	In MCF-7 and MDA-MB-231 cells, capsaicin induced endoplasmic reticulum (ER) stress via inositol-requiring 1 and Chop and induced autophagy, as demonstrated by microtubule-associated protein 1 light chain-3 (LC3) conversion.	Capsaicin	31-40	DNA damage inducible transcript 3	Homo sapiens	112-116	
19699254-6	2009	Capsaicin treatment triggered ER stress by increasing levels of IRE1, GADD153/Chop, GRP78/Bip, and activated caspase-4.	Capsaicin	0-9	DNA damage inducible transcript 3	Homo sapiens	78-82	
18533110-0	2008	Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: a microarray study.	Capsaicin	70-79	DNA damage inducible transcript 3	Homo sapiens	54-61	
19331147-7	2009	Immunostaining and confocal microscopic analysis also showed that capsaicin promoted cytoplasmic GADD153 expression and GRP78 nuclear translocation.	Capsaicin	66-75	DNA damage inducible transcript 3	Homo sapiens	97-104	
18533110-0	2008	Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: a microarray study.	Capsaicin	70-79	DNA damage inducible transcript 3	Homo sapiens	62-66	
18533110-6	2008	We then tested the contribution of GADD153/CHOP to protection against capsaicin-induced cell death using RNA interference.	Capsaicin	70-79	DNA damage inducible transcript 3	Homo sapiens	35-42	
18533110-7	2008	Blockage of GADD153/CHOP expression by small interfering RNA, significantly reduced capsaicin-induced cell death in PC-3 cells.	Capsaicin	84-93	DNA damage inducible transcript 3	Homo sapiens	12-19	
18533110-7	2008	Blockage of GADD153/CHOP expression by small interfering RNA, significantly reduced capsaicin-induced cell death in PC-3 cells.	Capsaicin	84-93	DNA damage inducible transcript 3	Homo sapiens	20-24	
35212819-5	2022	Employing alveolar epithelial cells with overexpression of the terminal ER stress signaling factor Chop or the IPF-associated surfactant protein C mutation (SPCDeltaexon4) in vitro, we observed a restoration of PACS2 levels upon treatment with CPS.	Capsaicin	244-247	DNA damage inducible transcript 3	Homo sapiens	99-103