PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30100034-10	2018	Capsaicin also decreased cleaved caspase-3, caspase-3/9, and Bax protein expression, effects abolished by TRPV1 blockade.	Capsaicin	0-9	BCL2-associated X protein	Mus musculus	61-64	
30272354-5	2018	In LM3 cells, capsaicin and sorafenib combination treatment achieved a markedly stronger induction of apoptosis by increasing caspase-3, Bax and poly(ADP-ribose) polymerase activity and inhibiting Bcl-2, and induction of autophagy by upregulating the levels of beclin-1 and LC3A/B II, enhancing P62 degradation.	Capsaicin	14-23	BCL2-associated X protein	Mus musculus	137-140	
27401946-5	2017	However, capsaicin pre-treatment significantly suppressed the spermatogenic cell death, oxidative stress (levels of MDA, PHGPx immunoreactivity, and Hsp72, PHGPx, and MnSOD mRNA) and apoptosis (levels of TUNEL-positive cells, and Bcl-xL and Bax mRNA) in testes by HS.	Capsaicin	9-18	BCL2-associated X protein	Mus musculus	241-244	
19002586-9	2008	Tumors from capsaicin treated mice demonstrated increased apoptosis, which was related to the activation of JNK and increased cytosolic protein expression of Bax, cytochrome c, AIF and cleaved caspase-3, as compared with controls.	Capsaicin	12-21	BCL2-associated X protein	Mus musculus	158-161	
23747734-3	2013	Intraperitoneal administration of CAP (10mg/kg body weight) to Swiss albino mice suppressed the development of lung carcinoma by amending the protein expressions of apoptotic regulators p53, Bcl-2, Bax and caspase-3.	Capsaicin	34-37	BCL2-associated X protein	Mus musculus	198-201	
20069556-6	2010	Exposure of capsaicin also causes increased accumulation of ubiquitinated proteins as wells as various target substrates of proteasome like p53 and Bax and p27.	Capsaicin	12-21	BCL2-associated X protein	Mus musculus	148-151	
17295509-9	2007	The induction of apoptosis in 3T3-L1 preadipocytes by capsaicin was mediated through the activation of caspase-3, Bax, and Bak, and then through the cleavage of PARP and the down-regulation of Bcl-2.	Capsaicin	54-63	BCL2-associated X protein	Mus musculus	114-117