PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31186689-9	2019	Furthermore, inhibiting capsaicin-induced autophagy promoted the activation of cleaved caspase-3 and PARP proteins, which are associated with apoptosis.	Capsaicin	24-33	poly(ADP-ribose) polymerase 1	Homo sapiens	101-105	
23433093-13	2013	Moreover, capsaicin induced disruption of the mitochondrial membrane potential as well as activation of caspase 9, 3 and poly-(ADP-ribose) polymerase in KB cells.	Capsaicin	10-19	poly(ADP-ribose) polymerase 1	Homo sapiens	121-149	
22226932-4	2012	Capsaicin treatment also activated delta-H2AX, ataxia telangiectasia mutated (ATM), DNA-dependent protein kinase catalytic subunit (DNA-PKcs), and poly(ADP-ribose) polymerase (PARP)-1.	Capsaicin	0-9	poly(ADP-ribose) polymerase 1	Homo sapiens	147-183	
22226932-6	2012	ATM inhibitors, including Ku55933 and caffeine, and the genetic or pharmacological inhibition of p53 prevented capsaicin-induced DNA-PKcs phosphorylation and stimulated PARP-1 cleavage, but had no effect on microtubule-associated protein light chain 3 (LC3)-II levels.	Capsaicin	111-120	poly(ADP-ribose) polymerase 1	Homo sapiens	169-175	
22226932-7	2012	Ly294002, a DNA-PKcs inhibitor, boosted the capsaicin-induced cleavage of PARP-1.	Capsaicin	44-53	poly(ADP-ribose) polymerase 1	Homo sapiens	74-80	
21300690-5	2011	Capsaicin significantly decreased mitochondria membrane potential, induced the cleavage of PARP-1, and decreased procaspase-7 expression in both cells.	Capsaicin	0-9	poly(ADP-ribose) polymerase 1	Homo sapiens	91-97