PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16387426-4 2006 The technique had to be suitable in clinical practice for determination of several factors involved in resistance to a given drug family, for example, fluoropyrimidines resistance factors: thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine kinase (TK), dihydrofolate reductase (DHFR), folylpolyglutamate synthetase (FPGS). fluoropyrimidines 151-168 folylpolyglutamate synthase Homo sapiens 310-339 21380490-2 2011 Given that LV effects are attributable to increased levels of reduced folate in cancer cells, we attempted here to show the in vivo role of folylpolyglutamate synthetase (FPGS), which stabilizes intracellular reduced folate, in the anticancer activities of oral fluoropyrimidines, UFT or S-1, combined with LV. fluoropyrimidines 262-279 folylpolyglutamate synthase Homo sapiens 140-169 21380490-2 2011 Given that LV effects are attributable to increased levels of reduced folate in cancer cells, we attempted here to show the in vivo role of folylpolyglutamate synthetase (FPGS), which stabilizes intracellular reduced folate, in the anticancer activities of oral fluoropyrimidines, UFT or S-1, combined with LV. fluoropyrimidines 262-279 folylpolyglutamate synthase Homo sapiens 171-175 16387426-4 2006 The technique had to be suitable in clinical practice for determination of several factors involved in resistance to a given drug family, for example, fluoropyrimidines resistance factors: thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine kinase (TK), dihydrofolate reductase (DHFR), folylpolyglutamate synthetase (FPGS). fluoropyrimidines 151-168 folylpolyglutamate synthase Homo sapiens 341-345