PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25583444-4	2015	Chemokines (CCL19 and CCL21) and KCa3.1 activator (1-ethyl-1,3-dihydro-2H-benzimidazol-2-one) induced plasma membrane hyperpolarization and K(+) efflux, which was blocked by 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole, suggesting that KCa3.1 carried larger conductance than the inward calcium release-activated calcium channel.	1-ethyl-2-benzimidazolinone	51-92	potassium calcium-activated channel subfamily N member 4	Homo sapiens	33-39	
26807020-6	2016	1-EBIO, an activator of SK4, induced outward K(+) current (ISK4) in SNU-1076 and OSC-19.	1-ethyl-2-benzimidazolinone	0-6	potassium calcium-activated channel subfamily N member 4	Homo sapiens	24-27	
26807020-8	2016	The 1-EBIO-induced current was abolished by TRAM-34, a selective SK4 blocker.	1-ethyl-2-benzimidazolinone	4-10	potassium calcium-activated channel subfamily N member 4	Homo sapiens	65-68	
25583444-4	2015	Chemokines (CCL19 and CCL21) and KCa3.1 activator (1-ethyl-1,3-dihydro-2H-benzimidazol-2-one) induced plasma membrane hyperpolarization and K(+) efflux, which was blocked by 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole, suggesting that KCa3.1 carried larger conductance than the inward calcium release-activated calcium channel.	1-ethyl-2-benzimidazolinone	51-92	potassium calcium-activated channel subfamily N member 4	Homo sapiens	238-244	
23492185-8	2013	In addition, the KCa3.1 activator 1-ethylbenzimidazolinone-induced membrane hyperpolarization and intracellular calcium increase in asthmatic human BSMCs were attenuated by TRAM-34.	1-ethyl-2-benzimidazolinone	34-58	potassium calcium-activated channel subfamily N member 4	Homo sapiens	17-23	
16766578-4	2006	Moreover, 1-ethyl-2-benzimidazolinone (1-EBIO), which is known to activate KCNN4, increased G(K) with no effect on G(Na).	1-ethyl-2-benzimidazolinone	10-37	potassium calcium-activated channel subfamily N member 4	Homo sapiens	75-80	
23776393-9	2013	Furthermore, KCa3.1 current, which was activated by clamping cells with 1 microM Ca(2+) and applying the KCa3.1 activator 1-ethyl-2-benzimidazolinone, was further augmented by TBHP, and inhibited by X/XO.	1-ethyl-2-benzimidazolinone	122-149	potassium calcium-activated channel subfamily N member 4	Homo sapiens	13-19	
23776393-9	2013	Furthermore, KCa3.1 current, which was activated by clamping cells with 1 microM Ca(2+) and applying the KCa3.1 activator 1-ethyl-2-benzimidazolinone, was further augmented by TBHP, and inhibited by X/XO.	1-ethyl-2-benzimidazolinone	122-149	potassium calcium-activated channel subfamily N member 4	Homo sapiens	105-111	
16766578-4	2006	Moreover, 1-ethyl-2-benzimidazolinone (1-EBIO), which is known to activate KCNN4, increased G(K) with no effect on G(Na).	1-ethyl-2-benzimidazolinone	39-45	potassium calcium-activated channel subfamily N member 4	Homo sapiens	75-80	
16766578-6	2006	Subsequent studies showed that 1-EBIO stimulates Na(+) transport in polarized monolayers without affecting intracellular Ca(2+) concentration ([Ca(2+)](i)), suggesting that the activity of KCNN4 might influence the rate of Na(+) absorption by contributing to G(K).	1-ethyl-2-benzimidazolinone	31-37	potassium calcium-activated channel subfamily N member 4	Homo sapiens	189-194	
17047984-6	2006	The secretory response to 1-ethyl-2-benzimidazolinone, an activator of the basolateral Ca(2+)-activated K(+) channel KCNN4, was similarly reduced by butyrate treatment.	1-ethyl-2-benzimidazolinone	26-53	potassium calcium-activated channel subfamily N member 4	Homo sapiens	117-122	
15241346-3	2004	OBJECTIVE: To confirm the identity of this channel as iKCA1 in human lung mast cells and to examine the effect of an iKCA1 opener, 1-ethyl-2-benzimidazolinone (1-EBIO), on Ca2+ influx and degranulation after IgE-dependent activation.	1-ethyl-2-benzimidazolinone	131-158	potassium calcium-activated channel subfamily N member 4	Homo sapiens	117-122	
12421833-0	2003	Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCaT keratinocytes.	1-ethyl-2-benzimidazolinone	79-106	potassium calcium-activated channel subfamily N member 4	Homo sapiens	34-38	
12421833-3	2003	When we incubated cells with the hIK1 opener, 1-ethyl-2-benzimidazolinone (1-EBIO), to investigate the cellular consequences of prolonged channel activity, an unexpected down-regulation of channels occurred within a few hours.	1-ethyl-2-benzimidazolinone	46-73	potassium calcium-activated channel subfamily N member 4	Homo sapiens	33-37	
12421833-3	2003	When we incubated cells with the hIK1 opener, 1-ethyl-2-benzimidazolinone (1-EBIO), to investigate the cellular consequences of prolonged channel activity, an unexpected down-regulation of channels occurred within a few hours.	1-ethyl-2-benzimidazolinone	75-81	potassium calcium-activated channel subfamily N member 4	Homo sapiens	33-37